Yazhen Wang
Sichuan University
6 Papers
Yazhen Wang is an academic researcher from Sichuan University. The author has contributed to research in topics: Chemistry & Immunogenic cell death. The author has an hindex of 2, co-authored 2 publications.
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Papers
Phagocyte-membrane-coated and laser-responsive nanoparticles control primary and metastatic cancer by inducing anti-tumor immunity.
Chuan Hu,Ting Lei,Yazhen Wang,Jun Cao,Xiaotong Yang,Lin Qin,Rui Liu,Yang Zhou,Fan Tong,Channakeshava Sokke Umeshappa,Huile Gao +10 more
TL;DR: This study provides a promising combinatorial strategy to trigger antitumor immunity in malignancies using M1-macrophage-membrane-coated nanoparticles having laser-responsive, size-changeable, on-demand drug release and prolonged circulation retention properties.
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A tumor-to-lymph procedure navigated versatile gel system for combinatorial therapy against tumor recurrence and metastasis.
Lin Qin,Jun Cao,Jun Cao,Kun Shao,Fan Tong,Zhihang Yang,Ting Lei,Yazhen Wang,Chuan Hu,Channakeshava Sokke Umeshappa,Huile Gao,Nicholas A. Peppas +11 more
TL;DR: In this article, a combinatorial therapy based on a α-cyclodextrin (CD)-based gel system, DOX/ICG/CpG-P-ss-M/CD, fabricated by encapsulating doxorubicin (DOX) and the photothermal agent indocyanine green (ICG), exhibited heat-responsive release of DOX and vaccine-like nanoparticles, along with chemotherapy-and phototherapy-generated abundant tumor-specific antigen storage in situ.
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Intelligent lesion blood–brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection
Xueqin He,Xiaorong Wang,Lianyi Yang,Zhihang Yang,Wenqi Yu,Yazhen Wang,Ruiqiang Li,Mei-He Chen,Huile Gao +8 more
TL;DR: In this paper , an ibuprofen and FK506 encapsulated drug co-delivery system (Ibu&[email protected]), which can target the receptor of advanced glycation endproducts (RAGE) and response to the high level of reactive oxygen species (ROS) in AD, was established.
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Rosmarinic Acid-Crosslinked Supramolecular Nanoassembly with Self-Regulated Photodynamic and Anti-Metastasis Properties for Synergistic Photoimmunotherapy.
Yang Zhou,Yiwei Zhang,Chaoqing Jiang,Yuxiu Chen,Fan Tong,Xiaotong Yang,Yazhen Wang,Xue Xia,Huile Gao +8 more
TL;DR: In this paper , the nanoassembly with self-regulated photodynamic and antimetastasis properties comprises three parts: chlorin e6-conjugated β-cyclodextrin (CD-Ce6) acts as the main PDT agent and ferrocene (Fc)-terminated phenylboronic acid-containing conjugates entering into the cavity of CD, as well as rosmarinic acid (RA)-bronic acid crosslinked shell.
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Challenges Coexist with Opportunities: Spatial Heterogeneity Expression of PD-L1 in Cancer Therapy.
Yazhen Wang,Yang Zhou,Lianyi Yang,Lei Lei,Bin He,Jun Cao,Huile Gao +6 more
TL;DR: An in‐depth analysis of the regulatory mechanisms and potential therapeutic targets of PD‐L1 is provided, seeking to offer a solid basis for future investigation and to offer a novel perspective on potential PD‐L1 therapeutics strategies.
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