Yazeed Jamalat
Dalian Medical University
6 Papers
7 Citations
Yazeed Jamalat is an academic researcher from Dalian Medical University. The author has contributed to research in topics: Apoptosis & Lactobacillus rhamnosus. The author has an hindex of 5, co-authored 6 publications.
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Papers
miR-421 up-regulation by the oleanolic acid derivative K73-03 regulates epigenetically SPINK1 transcription in pancreatic cancer cells leading to metabolic changes and enhanced apoptosis.
Abdullah Shopit,Xiaodong Li,Zhongyuan Tang,Mohammed Awsh,Loubna Shobet,Mengyue Niu,Hongyan Wang,Haithm Mousa,Mohammed Alshwmi,Tsehaye Tesfaldet,Yaser Gamallat,Hailong Li,Peng Chu,Nisar Ahmad,Yazeed Jamalat,Jie Ai,Eskandar Qaed,Marwan Almoiliqy,Shisheng Wang,Zeyao Tang +19 more
TL;DR: The findings indicated that K73-03 inhibited the mitochondrial function that led to inducing autophagy and apoptosis through epigenetic SPINK1 down-regulation via miR-421 up-regulation in pancreatic cancer.
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The immune-modulation and gut microbiome structure modification associated with long-term dietary supplementation of Lactobacillus rhamnosus using 16S rRNA sequencing analysis
Yaser Gamallat,Xiaomeng Ren,Abdo Meyiah,Meiqi Li,Xinxiu Ren,Yazeed Jamalat,Siyuan Song,Luhan Xie,Bashir Ahmad,Abdullah Shopit,Haithm Mousa,Yufang Ma,Yi Xin,Dapeng Ding +13 more
TL;DR: The findings demonstrate that the LBR dietary supplementation found to be beneficially modulating the immune-response, enhances lipoprotein metabolism, and ameliorates the microbial composition structure and functions.
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Natural gypenosides: targeting cancer through different molecular pathways
Bashir Ahmad,Suliman Khan,Ghulam Nabi,Yaser Gamallat,Pengyu Su,Yazeed Jamalat,Pengfei Duan,Lunguang Yao +7 more
TL;DR: Gyp studies on cancer are summarized to serve as a reference for further research and clinical trials and inhibit invasion, migration, metastasis, and proliferation and induce apoptosis in different cancers, including oral, lung, colorectal, hepatocellular, and leukemic cancers.
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Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Hongyan Wang,Jie Ai,Abdullah Shopit,Mengyue Niu,Nisar Ahmed,Tsehaye Tesfaldet,Zhongyuan Tang,Xiaodong Li,Yazeed Jamalat,Peng Chu,Jinyong Peng,Xiaodong Ma,Eskandar Qaed,Guozhu Han,Weisheng Zhang,Jun Wang,Zeyao Tang +16 more
TL;DR: PCr has protective effect on INS-1 cells in vitro and in vivo, relying on AKT mediated STAT3/ Cyp-D pathway to inhibit oxidative stress and restore mitochondrial function, signifying that PCr might become an emerging candidate for the cure of diabetic pancreatic cancer β-cell damage.
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Phosphocreatine attenuates endoplasmic reticulum stress-mediated hepatocellular apoptosis ameliorates insulin resistance in diabetes model.
Yazeed Jamalat,Yaser Gamallat,Pires Sanches Jaceline Gislaine,Abdo Meyiah,Abdullah Shopit,Hailong Li,Bashir Ahmed,Peng Chu,Hongyang Wang,Xiaodong Li,Jinyong Peng,Xiaodong Ma,Zeyao Tang +12 more
TL;DR: Investigating the protective effect of PCr on the liver-injury-associated with DM revealed that treating with PCr in diabetes-associated liver injury models decreased blood glucose level and possess protective effect in-vitro and in- vivo, which could be suggested as potential therapeutic strategy for diabetes associated liver injury patients.
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