Yawei Li
Harbin Medical University
5 Papers
6 Citations
Yawei Li is an academic researcher from Harbin Medical University. The author has contributed to research in topics: Homologous recombination & Cancer. The author has an hindex of 2, co-authored 5 publications.
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Papers
Individualized lncRNA differential expression profile reveals heterogeneity of breast cancer
Zhangxiang Zhao,Yingying Guo,Yaoyao Liu,Lichun Sun,Bo Chen,Chengyu Wang,Tingting Chen,Yuquan Wang,Yawei Li,Qi Dong,Liqiang Ai,Ran Wang,Yunyan Gu,Xia Li +13 more
TL;DR: Zhang et al. as discussed by the authors constructed an individualized differentially expressed lncRNA (IDElncRNA) profile for breast invasive carcinoma (BRCA) using the method of LncRNA Individualization (LncRIndiv).
Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics
Yawei Li,H Sun,Congyi Zhang,J Liu,H Zhang,F Fan,Robert A. Everley,X Ning,Y Sun,J Hu,Jiewu Zhang,W Ye,X Qiu,S Dai,B Liu,Huizhe Xu,Songbin Fu,Steven P. Gygi,Chunshui Zhou +18 more
TL;DR: An important role is identified in promoting DNA double-stand break repair via facilitating DNA homologous recombination processes and the great potential of TCTP as a drug target to enhance conventional chemotherapy for cancer patients with high levels of T CTP expression is highlighted.
Discovering a qualitative transcriptional signature of homologous recombination defectiveness for prostate cancer
Yawei Li,Zhangxiang Zhao,Liqiang Ai,Yuquan Wang,Kaidong Liu,Bo Chen,Tingting Chen,Shuping Zhuang,Huanhuan Xu,Min Zou,Yunyan Gu,Xia Li +11 more
TL;DR: Wang et al. as mentioned in this paper developed a transcriptional homologous recombination defectiveness (HRDness) signature, comprising 16 gene pairs (16-GPS), for prostate cancer by a relative expression ordering (REO)-based discovery procedure.
9
Revealing biomarkers associated with PARP inhibitors based on genetic interactions in cancer genome.
Qi Dong,Mingyue Liu,Bo Chen,Zhangxiang Zhao,Tingting Chen,Chengyu Wang,Shuping Zhuang,Yawei Li,Yuquan Wang,Liqiang Ai,Yaoyao Liu,Haihai Liang,Lishuang Qi,Yunyan Gu +13 more
TL;DR: In this article, the authors proposed a method to identify PARP1/2/3-related GIs using CRISPR/Cas9 and RNA interference functional screens, and identified 41 candidate resistant and 130 candidate sensitive PARPi-response related genes.
4
A transcriptional signature detects homologous recombination deficiency in pancreatic cancer at the individual level.
Shuping Zhuang,Tingting Chen,Yawei Li,Yuquan Wang,Liqiang Ai,Yiding Geng,Min Zou,Kaidong Liu,Huanhuan Xu,Linzhu Wang,Zhangxiang Zhao,Zhiqiang Chang,Yunyan Gu +12 more
TL;DR: Based on a relative expression ordering (REO)-based algorithm, this paper developed an HRD signature including 24 gene pairs (24-GPS) using PC transcriptional profiles from The Cancer Genome Atlas (TCGA).