Yawei Li
5 Papers
Yawei Li is an academic researcher. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 1, co-authored 3 publications.
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Papers
Systematic exploration of the underlying mechanism of gemcitabine resistance in pancreatic adenocarcinoma
Kaidong Liu,Yiding Geng,Linzhu Wang,Huanhuan Xu,Min Zou,Yawei Li,Zhangxiang Zhao,Ting Chen,Fengyan Xu,Liang Sun,Shuliang Wu,Yunyan Gu +11 more
TL;DR: A transcriptome‐based gemcitabine signature consisting of 28 gene pairs that could robustly determine whether PDAC is resistant or sensitive to gem citabine, and may be an auxiliary tool for clinical treatment is developed.
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Upregulation of CXCL1 and LY9 contributes to BRCAness in ovarian cancer and mediates response to PARPi and immune checkpoint blockade
Ting Chen,Tong Yu,Shuping Zhuang,Yiding Geng,Jun-Tian Xue,Jiayi Wang,Liqiang Ai,Bo Chen,Zhangxiang Zhao,Yawei Li,Jinghao Wang,Haihai Liang,Yan Xu,Yunyan Gu +13 more
TL;DR: 2-GPS could robustly predict BRCAness OvCa at the individual level and extend the population who may benefit from PARP inhibitors.
7
Individualized detection of TMPRSS2-ERG fusion status in prostate cancer: a rank-based qualitative transcriptome signature
Yawei Li,Hang Su,Kai Liu,Zhangxiang Zhao,Yuquan Wang,Bo Chen,Jie Xia,Huating Yuan,De-Shuang Huang,Yunyan Gu +9 more
TL;DR: 5-ERG-mRPs can robustly detect T2E fusion in PC at the individual level, which can be used on any gene measurement platform without specific normalization procedures, and may serve as an auxiliary tool for PC patient management.
Multi-omics integration analysis unveils heterogeneity in breast cancer at the individual level.
Zhangxiang Zhao,Tongzhu Jin,Qi Dong,Mingyue Liu,Jiayu Guo,Xiaoying Song,Yawei Li,Huiming Han,Haihai Liang,Yunyan Gu +9 more
TL;DR: The integration of multi-omics data at the individual level provides a powerful framework for elucidating the heterogeneity of breast cancer.
A genetic map of the chromatin regulators to drug response in cancer cells
Bo Chen,Pengfei Li,Mingyue Liu,Kaidong Liu,Min Zou,Yiding Geng,Shuping Zhuang,Huanhuan Xu,Linzhu Wang,Ting Chen,Yawei Li,Zhangxiang Zhao,Lishuang Qi,Yunyan Gu +13 more
TL;DR: Wang et al. as mentioned in this paper developed a method to identify potential drug response-related Chromatin regulators (CRs) genetic interactions for specific cancer types by integrating the screen of CRISPR-Cas9 and pharmacogenomic response datasets.