Yasuhiro Moriyama
Osaka University
13 Papers
446 Citations
Yasuhiro Moriyama is an academic researcher from Osaka University. The author has contributed to research in topics: Receptor tyrosine kinase & Biology. The author has an hindex of 10, co-authored 13 publications.
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Papers
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.
Seiichi Hirota,Koji Isozaki,Yasuhiro Moriyama,Koji Hashimoto,Toshirou Nishida,Shingo Ishiguro,Kiyoshi Kawano,Masato Hanada,Akihiko Kurata,Masashi Takeda,Ghulam Muhammad Tunio,Yuji Matsuzawa,Yuzuru Kanakura,Yasuhisa Shinomura,Yukihiko Kitamura +14 more
TL;DR: Sequencing of c-kit complementary DNA from five GISTs revealed mutations in the region between the transmembrane and tyrosine kinase domains, suggesting that the mutations contribute to tumor development.
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Involvement of transcription factor encoded by the mi locus in the expression of c-kit receptor tyrosine kinase in cultured mast cells of mice
Tohru Tsujimura,Eiichi Morii,Masami Nozaki,Koji Hashimoto,Yasuhiro Moriyama,Kimiko Takebayashi,Taizo Kondo,Yuzuru Kanakura,Yukihiko Kitamura +8 more
TL;DR: The involvement of (+)-MITF in the c-kit transactivation appeared to be specific to the mast cell lineage.
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One-step purification of Escherichia coli H(+)-ATPase (F0F1) and its reconstitution into liposomes with neurotransmitter transporters.
TL;DR: Proteoliposomes reconstituted with F0F1 and solubilized transporters from chromaffin granules or synaptic vesicle membranes could transport serotonin, dopamine, and norepinephrine dependent on ATP hydrolysis.
131
Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain
Tohru Tsujimura,Masahiro Morimoto,Koji Hashimoto,Yasuhiro Moriyama,Hitoshi Kitayama,Yuji Matsuzawa,Yukihiko Kitamura,Yuzuru Kanakura +7 more
TL;DR: The deletion of seven amino acids at the juxtamembrane domain appeared to be a new activating mutation of KIT that might be involved in neoplastic growth of mast cells.
114
Growth response of acute myeloblastic leukemia cells to recombinant human thrombopoietin
Itaru Matsumura,Yuzuru Kanakura,Takashi Kato,Hirokazu Ikeda,Jun Ishikawa,Yoko Horikawa,Koji Hashimoto,Yasuhiro Moriyama,Tohru Tsujimura,Tetsuo Nishiura +9 more
TL;DR: Results suggested that c-mpl may be functional in terms of supporting proliferation of various types of AML cells and that TPO may contribute, at least in part, to abnormal growth of the cells, especially in combination with other hematopoietic growth factors.
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