Yasuhiko Suzuki
International Institute of Minnesota
315 Papers
2.2K Citations
Yasuhiko Suzuki is an academic researcher from International Institute of Minnesota. The author has contributed to research in topics: Mycobacterium tuberculosis & Tuberculosis. The author has an hindex of 43, co-authored 314 publications. Previous affiliations of Yasuhiko Suzuki include Mitsui Chemicals & Osaka Bioscience Institute.
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Papers
A novel method for simple detection of mutations conferring drug resistance in Mycobacterium leprae, based on a DNA microarray, and its applicability in developing countries.
Masanori Matsuoka,Khin Saw Aye,Kyaw Kyaw,Esterlina V. Tan,Ma. Victoria F. Balagon,Paul Saunderson,Robert H. Gelber,Masanao Makino,Chie Nakajima,Yasuhiko Suzuki +9 more
TL;DR: The high concordance of the results obtained by this method with the results of nucleotide sequencing strongly supports the applicability of the LDS-DA as a drug susceptibility test in place of sequencing, a time-consuming and costly procedure.
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Alteration of ribosomes and RNA polymerase in drug-resistant clinical isolates of Mycobacterium tuberculosis.
TL;DR: The biochemical mechanism of resistance to kanamycin, viomycin, and rifampin in five clinical isolates of Mycobacterium tuberculosis was studied and alteration of RNA polymerase was attributed to altered ribosomes.
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Cooperation of PD-1 and LAG-3 in the exhaustion of CD4 + and CD8 + T cells during bovine leukemia virus infection
Tomohiro Okagawa,Satoru Konnai,Asami Nishimori,Naoya Maekawa,Shinya Goto,Ryoyo Ikebuchi,Ryoyo Ikebuchi,Junko Kohara,Yasuhiko Suzuki,Shinji Yamada,Yukinari Kato,Shiro Murata,Kazuhiko Ohashi +12 more
TL;DR: Results indicate that PD-1 and LAG-3 cooperatively mediate the functional exhaustion of CD4+ and CD8+ T cells and are associated with the development of B-cell lymphoma in BLV-infected cattle.
Prostaglandin E2 Induction Suppresses the Th1 Immune Responses in Cattle with Johne's Disease
Yamato Sajiki,Satoru Konnai,Tomohiro Okagawa,Asami Nishimori,Naoya Maekawa,Shinya Goto,Ryoyo Ikebuchi,Reiko Nagata,Satoko Kawaji,Yumiko Kagawa,Shinji Yamada,Yukinari Kato,Chie Nakajima,Yasuhiko Suzuki,Shiro Murata,Yasuyuki Mori,Kazuhiko Ohashi +16 more
TL;DR: Functional and kinetic analyses of PGE2 were performed and combined treatment with a COX-2 inhibitor and anti-PD-L1 antibodies enhanced J-PPD-stimulated CD8+ T-cell proliferation in vitro, suggesting that the blockade of both pathways is a potential therapeutic strategy to control Johne's disease.
31
Mycobacterium bovis infection at the interface between domestic and wild animals in Zambia
Mudenda B. Hang'ombe,Musso Munyeme,Chie Nakajima,Yukari Fukushima,Haruka Suzuki,Wigganson Matandiko,Akihiro Ishii,Aaron S. Mweene,Yasuhiko Suzuki +8 more
TL;DR: These results provide strong evidence of M. bovis strains transfer between cattle and lechwe, with the latter having developed into a sylvatic reservoir host.