7 Papers
Yaqi Wang is an academic researcher from Nanjing University of Chinese Medicine. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 1, co-authored 1 publications.
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Papers
Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates
Yu-Qing Du,Zhen Liang,Sheng Wang,Dong Sun,Xiaofeng Wang,Soon Yi Liew,Shuaiyao Lu,Shuangshuang Wu,Yong Jiang,Yaqi Wang,Boya Zhang,Wenhai Yu,Zhiying Lu,Yue Pu,Yun-Jin Zhang,Haiting Long,Shanshan Xiao,Rui Liang,Zhengyuan Zhang,Jingyang Guan,Jinlin Wang,Huixia Ren,Yanling Wei,Jiaxu Zhao,Shicheng Sun,Tengli Liu,Gaofan Meng,Lei Wang,Jiabin Gu,Tao Wang,Yinan Liu,Cheng Li,Chao Tang,Zhong-yang Shen,Xiaozhong Peng,Hongkui Deng +35 more
TL;DR: This study generated islets from human chemically induced pluripotent stem cells (hCiPSC-islets) and shows that a one-dose intraportal infusion into diabetic non-human primates effectively restored endogenous insulin secretion and improved glycemic control.
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An acidic heteropolysaccharide from Lycii fructus: Purification, characterization, neurotrophic and neuroprotective activities in vitro.
Fang Zhang,Xia Zhang,Xia Zhang,Sheng Guo,Funing Cao,Xiaofei Zhang,Yaqi Wang,Jiazheng Liu,Bowen Qian,Yichao Yan,Peidong Chen,Chunlei Xu,Chunmei Liu,Dawei Qian,Jin-Ao Duan +14 more
TL;DR: LFP-1 promoted neuronal differentiation and neurite outgrowth in vitro in PC12 cell models and had a significantly protective effect against 1-methyl-4-phenylpyridiniumion (MPP+)-induced neurotoxicity in PD model PC12 cells, unambiguously indicated the neurotrophic and neuroprotective activities of LFP- 1.
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Restricting Bond Rotations by Ring Fusion: A Novel Molecular Design Strategy to Improve Photodynamic Antibacterial Efficacy of AIE Photosensitizers.
TL;DR: Wang et al. as discussed by the authors proposed that if the rotation of some bonds in AIE-PSs is restricted, the nonradiative decay could be further suppressed to boost the generation of fluorescence and ROS, so as to improve their antibacterial efficacy.
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Structural Characteristics of Rehmannia glutinosa Polysaccharides Treated Using Different Decolorization Processes and Their Antioxidant Effects in Intestinal Epithelial Cells
Heng Ren,Zhongyuan Li,Rui Gao,Tongxi Zhao,Dan-hong Luo,Zihao Yu,Shu Ai Zhang,Chen Qi,Yaqi Wang,H.-Z. Qiao,Yaoming Cui,Liping Gan,Peng-Yun Wang,Jinrong Wang +13 more
TL;DR: In this article , two purified Rehmannia glutinosa polysaccharides (RGP−1−A and RGP−2−A) were obtained after decolorization using the AB-8 macroporous resin and H2O2, respectively.
An AIE photosensitizer with unquenched fluorescence based on nitrobenzoic acid for tumor-targeting and image-guided photodynamic therapy.
TL;DR: Biotin-TTVBA is developed, a tumor-targeting aggregation-induced emission photosensitizer (AIE-PS), by binding TTVBA (a nitrobenzoic acid-based AIE-PS with a free carboxylic acid group) to biotin, resulting in enhanced antitumor activity against tumor cells and a decreased IC50 value.
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