Yanling Dai
Nanjing University
16 Papers
182 Citations
Yanling Dai is an academic researcher from Nanjing University. The author has contributed to research in topics: Enantioselective synthesis & Trifluoromethyl. The author has an hindex of 7, co-authored 16 publications.
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Papers
Asymmetric synthesis of quaternary α-fluoro-β-keto-amines via detrifluoroacetylative Mannich reactions.
TL;DR: Efficient asymmetric detrifluoroacetylative Mannich addition reactions between 2-fluoro-1,3-di-ketones/hydrates and chiral N-sulfinyl-imines via C-C bond cleavage were reported, which afforded C-F quaternary α- fluoro-β-keto-amines with excellent yields and high diastereoselectivity.
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Synthesis of trifluoromethyl-containing vicinal diamines by asymmetric decarboxylative mannich addition reactions.
Lingmin Wu,Chen Xie,Haibo Mei,Yanling Dai,Jianlin Han,Vadim A. Soloshonok,Vadim A. Soloshonok,Yi Pan +7 more
TL;DR: These reactions proceed with excellent diastereoselectivities and good chemical yields, providing a practical method for preparation of trifluoromethyl-containing vicinal diamines.
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Catalytic asymmetric detrifluoroacetylative aldol reactions of aliphatic aldehydes for construction of C-F quaternary stereogenic centers
Lijun Zhang,Chen Xie,Yanling Dai,Haibo Mei,Jianlin Han,Vadim A. Soloshonokcd,Vadim A. Soloshonokcd,Yi Pan +7 more
TL;DR: In this article, the authors demonstrate that the reactions of in situ generated fluoro-enolates with a range of aliphatic aldehydes can be successfully performed using asymmetric catalyst derived from chiral ligand and Cu(OTf) 2.
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Asymmetric Synthesis of Quaternary α-Fluoro-β-keto-amines via Detrifluoroacetylative Mannich Reactions.
TL;DR: In this article, a simple procedure for the synthesis of α-fluoro-β-keto-amines (III) and (VI) by detrifluoroacetylative Mannich reaction of keto-hydrates (I) and with imines (II).
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Mannich-Type Addition Reactions between Lithium Derivatives of Benzo[d]thiazoles and N-tert-Butylsulfinyl-3,3,3-trifluoroacetaldimine: Convenient Generalized Synthesis of Bis(benzothiazole)s
TL;DR: In this paper, the anomalous outcome of the Mannich-type reaction of N-tert-butylsulfinyl-3,3-3-trifluoroacetaldimine and Li derivatives of benzo[d]thiazoles was described.
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