Yanjia Chen
Shanghai Jiao Tong University
30 Papers
54 Citations
Yanjia Chen is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Medicine & Heart failure. The author has an hindex of 10, co-authored 20 publications.
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Papers
Bone marrow‑derived mesenchymal stem cells rescue injured H9c2 cells via transferring intact mitochondria through tunneling nanotubes in an in vitro simulated ischemia/reperfusion model
TL;DR: The anti-apoptotic ability of BM-MSCs may be partially attributed to the recovery of mitochondrial dysfunction in SI/R, and the formation of TNTs appears to be involved in this action of mitochondrial transfer between adjacent cells.
Decreased circulating catestatin levels are associated with coronary artery disease: The emerging anti-inflammatory role.
Yanjia Chen,Xiaoqun Wang,C.D Yang,Xiuxiu Su,Wenbo Yang,Yang Dai,Hui Han,Jie Jiang,Lin Lu,Haibo Wang,Qiujing Chen,Wei Jin +11 more
TL;DR: Serum CST concentration is lower in CAD patients and is inversely associated with the severity of atherosclerosis, and CST acts as a novel anti-atherogenic peptide that inhibits inflammatory response and EC-leukocyte interactions via an ACE2-dependent mechanism.
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Renal recruitment of B lymphocytes exacerbates tubulointerstitial fibrosis by promoting monocyte mobilization and infiltration after unilateral ureteral obstruction.
Hui Han,Jinzhou Zhu,Yaqiong Wang,Zhengbin Zhu,Yanjia Chen,Lin Lu,Wei Jin,Xiaoxiang Yan,Ruiyan Zhang +8 more
TL;DR: Early‐stage accumulation of B cells in the kidney accelerated monocyte/macrophage mobilization and infiltration, aggravating the fibrosis resulting from acutely induced kidney nephropathy.
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MicroRNA-19b-1 reverses ischaemia-induced heart failure by inhibiting cardiomyocyte apoptosis and targeting Bcl2 l11/BIM
TL;DR: An essential role of miR-19b-1 in ischaemia-induced heart failure is revealed, which not only attenuated the infarct size but also ameliorated heart failure after myocardial infarction, including the changes in the left ventricular ejection fraction and volume load.
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p -Cresyl sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular smooth muscle cells
TL;DR: PCS played a vital role in promoting atherogenesis and disturbing the stability of formed plaques probably by targeting VSMCs in mice that underwent 5/6 nephrectomy.
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