Yang Zhou
Sichuan University
31 Papers
Yang Zhou is an academic researcher from Sichuan University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 10, co-authored 17 publications.
Chat about Author
Papers
Size-Tunable Strategies for a Tumor Targeted Drug Delivery System.
TL;DR: A series of stimuli-induced aggregation and shrinkage strategies for tumor targeted drug delivery, which can significantly increase the retention and penetration of nanodrugs in tumor sites at the same time, thus promoting treatment efficacy are summarized.
351
Rethinking CRITID Procedure of Brain Targeting Drug Delivery: Circulation, Blood Brain Barrier Recognition, Intracellular Transport, Diseased Cell Targeting, Internalization, and Drug Release
TL;DR: The typical delivery process of a systemically administrated NPs‐based brain‐targeting drug delivery system is analyzed and a six‐step CRITID delivery cascade is proposed: circulation in systemic blood, recognizing receptor on blood‐brain barrier, intracellular transport, diseased cell targeting after entering into parenchyma, internalization by diseased cells, and finally intrACEllular drug release.
140
The progress and perspective of nanoparticle-enabled tumor metastasis treatment.
TL;DR: As a promising treatment, the application of immunotherapy in tumor metastasis treatment is introduced, and strategies that stimulating immune response are reviewed, including chemotherapy, photothermal therapy, photodynamic Therapy, ferroptosis, sonodynamic therapy, and nanovaccines.
139
Phagocyte-membrane-coated and laser-responsive nanoparticles control primary and metastatic cancer by inducing anti-tumor immunity.
Chuan Hu,Ting Lei,Yazhen Wang,Jun Cao,Xiaotong Yang,Lin Qin,Rui Liu,Yang Zhou,Fan Tong,Channakeshava Sokke Umeshappa,Huile Gao +10 more
TL;DR: This study provides a promising combinatorial strategy to trigger antitumor immunity in malignancies using M1-macrophage-membrane-coated nanoparticles having laser-responsive, size-changeable, on-demand drug release and prolonged circulation retention properties.
129
The protein corona hampers the transcytosis of transferrin-modified nanoparticles through blood-brain barrier and attenuates their targeting ability to brain tumor.
Wei Xiao,Yazhen Wang,Huilin Zhang,Yuwei Liu,Rou Xie,Xueqin He,Yang Zhou,Luqing Liang,Huile Gao +8 more
TL;DR: In this article, transferrin (Tf) was coupled with nanoparticles to evaluate BBB transcytosis and brain tumor targeting ability, and different impacts of the in vitro and in vivo protein corona on receptor targeting, lysosomal escape, and BBBtranscytotic processes were found.
123