26 Papers
148 Citations
Yang Yang is an academic researcher from Center for Drug Evaluation and Research. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 14, co-authored 23 publications. Previous affiliations of Yang Yang include Food and Drug Administration & Peking University.
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Papers
Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
Murali K. Matta,Jeffry Florian,Robbert Zusterzeel,Nageswara Rao Pilli,Vikram Patel,Donna A. Volpe,Yang Yang,Luke Oh,Edward D. Bashaw,Issam Zineh,Carlos Sanabria,Sarah Kemp,Anthony Godfrey,Steven Adah,Sergio G. Coelho,Jian Wang,Lesley Anne Furlong,Charles J. Ganley,Theresa Michele,David G. Strauss +19 more
TL;DR: The systemic absorption and pharmacokinetics of the 6 active ingredients of sunscreen active ingredients in 4 sunscreen products under single- and maximal-use conditions were assessed to determine the systemic absorption of additional active ingredients and how quickly systemic exposure exceeds 0.5 ng/mL.
Effect of Size, Surface Charge, and Hydrophobicity of Poly(amidoamine) Dendrimers on Their Skin Penetration
Yang Yang,Suhair Sunoqrot,Chelsea Stowell,Jingli Ji,Chan Woo Lee,Jin Woong Kim,Seema A. Khan,Seungpyo Hong +7 more
TL;DR: It is reported that size, surface charge, and hydrophobicity directly dictate the permeation route and efficiency of dendrimer translocation across the skin layers, providing a design guideline for engineering PAMAM d endrimers as a potential transdermal delivery vector.
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Development of performance matrix for generic product equivalence of acyclovir topical creams
Yellela S.R. Krishnaiah,Xiaoming Xu,Ziyaur Rahman,Yang Yang,Usha Katragadda,Robert Lionberger,John R. Peters,Kathleen Uhl,Mansoor A. Khan +8 more
TL;DR: Generic acyclovir creams can be manufactured to obtain identical performance as that of RLD with Q1/Q2/Q3 with in vitro drug release studies against RLD.
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Assessing impact of formulation and process variables on in-vitro performance of directly compressed abuse deterrent formulations
Ziyaur Rahman,Yang Yang,Maxwell Korang-Yeboah,Akhtar Siddiqui,Xiaoming Xu,Muhammad Ashraf,Mansoor A. Khan,Mansoor A. Khan +7 more
TL;DR: The study indicated some advantages of ADF product compared to non-ADF prepared by direct compression, however, the ADF should not be viewed as abuse proof product rather as incrementally improved product.
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Influence of drug loading and type of ointment base on the in vitro performance of acyclovir ophthalmic ointment
Manar Al-Ghabeish,Xiaoming Xu,Yellela S.R. Krishnaiah,Ziyaur Rahman,Yang Yang,Mansoor A. Khan +5 more
TL;DR: It appears that drug release from the ointment is controlling acyclovir transport through the cornea, and enhanced in vitro transcorneal permeation relative to the in vitro drug release underscores the importance of the interplay between the physiology of the ocular tissue and ointments formulation.
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