Yang Yan
East China Normal University
15 Papers
4 Citations
Yang Yan is an academic researcher from East China Normal University. The author has contributed to research in topics: Photothermal therapy & Chemistry. The author has an hindex of 9, co-authored 15 publications.
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Papers
The fluorination effect of fluoroamphiphiles in cytosolic protein delivery.
TL;DR: A type of polymers, fluoroamphiphiles, acting as chemical chaperones that can facilitate the import of proteins into the inner compartment, i.e. cytosol, of cells are presented.
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Autophagy inhibition enabled efficient photothermal therapy at a mild temperature.
TL;DR: Autophagy was activated in cancer cells underwent photothermal therapy and the inhibition of autophagy significantly enhanced the efficacy of photothermal killing of cancer cells, leading to efficient tumor suppression at a mild temperature.
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Dendrimer-Templated Ultrasmall and Multifunctional Photothermal Agents for Efficient Tumor Ablation
TL;DR: This study used a dendrimer as a template to synthesize ultrasmall photothermal agents and further modified them with multifunctional groups and revealed RGD-modified DENPs efficiently reduced the tumor growth upon near-infrared irradiation.
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Fluoroalkylation promotes cytosolic peptide delivery.
TL;DR: This study provides an efficient fluorination strategy to promote the cytosolic delivery of peptides by decoration of a fluorous tag on the terminal of cargo peptides and efficiently delivered a proapoptotic peptide that efficiently inhibited tumor growth in vivo.
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One stone with two birds: Phytic acid-capped platinum nanoparticles for targeted combination therapy of bone tumors.
Zhengjie Zhou,Tianqi Fan,Yang Yan,Song Zhang,Yi Zhou,Hanbin Deng,Xiaopan Cai,Jianru Xiao,Dianwen Song,Qiang Zhang,Yiyun Cheng +10 more
TL;DR: A naturally occurring phytic acid (PA) with both bone-targeting capability and anticancer activity is reported, and PA-capped platinum nanoparticles showed high affinity to hydroxyapatite in vitro and in vivo, and maintained both the inherent anticancer ability of PA and photothermal effect of Platinum nanoparticles.
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