Yang Liu
University Health Network
14 Papers
185 Citations
Yang Liu is an academic researcher from University Health Network. The author has contributed to research in topics: Spinal cord injury & Neural stem cell. The author has an hindex of 9, co-authored 12 publications. Previous affiliations of Yang Liu include Toronto Western Hospital.
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Papers
Self-assembling peptides optimize the post-traumatic milieu and synergistically enhance the effects of neural stem cell therapy after cervical spinal cord injury.
TL;DR: Injecting SAPs after SCI enhances subsequent NPC survival, integration and differentiation and improves functional recovery, a promising finding for those with SCIs.
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Human Oligodendrogenic Neural Progenitor Cells Delivered with Chondroitinase ABC Facilitate Functional Repair of Chronic Spinal Cord Injury.
Satoshi Nori,Mohamad Khazaei,Christopher S. Ahuja,Kazuya Yokota,Jan Eric Ahlfors,Yang Liu,Jian Wang,Shinsuke Shibata,Jonathon Chon Teng Chio,Marian H. Hettiaratchi,Tobias Führmann,Molly S. Shoichet,Michael G. Fehlings +12 more
TL;DR: In this paper, a neural progenitor cell (NPC) and chondroitinase ABC (ChABC) combinatorial therapy was used for chronic spinal cord injury (SCI) treatment.
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Synergistic effects of self-assembling peptide and neural stem/progenitor cells to promote tissue repair and forelimb functional recovery in cervical spinal cord injury.
Motoyuki Iwasaki,Jared T. Wilcox,Yusuke Nishimura,Klaus Zweckberger,Hidenori Suzuki,Jian Wang,Yang Liu,Spyridon K. Karadimas,Michael G. Fehlings +8 more
TL;DR: In this paper, the authors examined the synergistic effect of self-assembling peptide (SAP) molecules and NSCs in a clinically-relevant model of contusive/compressive cervical SCI.
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An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury.
Yang Liu,Sarah A. Figley,Sarah A. Figley,S. Kaye Spratt,Gary Lee,Dale Ando,Richard T. Surosky,Michael G. Fehlings,Michael G. Fehlings +8 more
TL;DR: The data suggest that activation of VEGF-A via the administration of an engineered ZFP transcription factor holds promise as a therapy for SCI and potentially other forms of neurotrauma.
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An in vitro model of neurotrauma in organotypic spinal cord cultures from adult mice.
Andrei V. Krassioukov,Alun Ackery,Alun Ackery,Gwen Schwartz,Gwen Schwartz,Yana Adamchik,Yang Liu,Michael G. Fehlings,Michael G. Fehlings +8 more
TL;DR: This novel in vitro model of SCI is easy to reproduce, will facilitate the examination of post-trauma cell death mechanisms and the neuroprotective effects of pharmacological agents and aid in the study of transgenic murine models.
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