Yan Zhu
Anhui Medical University
19 Papers
128 Citations
Yan Zhu is an academic researcher from Anhui Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 10, co-authored 13 publications.
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Papers
Gene-gene and gene-sex epistatic interactions of MiR146a, IRF5, IKZF1, ETS1 and IL21 in systemic lupus erythematosus.
Rui-Xue Leng,Wei Wang,Han Cen,Mo Zhou,Chen-Chen Feng,Yan Zhu,Xiao-Ke Yang,Mei Yang,Yu Zhai,Bao-Zhu Li,Xiao-Song Wang,Rui Li,Gui-Mei Chen,Hong Chen,Hai-Feng Pan,Dong-Qing Ye +15 more
TL;DR: This study identified novel gene–gene/gene-sex interactions in lupus and highlights sex, interferon pathway, and Th17/B cells as important contributors to the pathogenesis of SLE.
Serum levels of cytokines in systemic lupus erythematosus : Association study in a Chinese population.
TL;DR: In this paper, the authors investigated serum levels of cytokines (IL-19, IL-24 and IL-26) in systemic lupus erythematosus (SLE) patients compared with normal controls in a Chinese population.
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Therapeutic potential of tyrosine kinase 2 in autoimmunity.
Yan Liang,Yan Zhu,Yi Xia,Hui Peng,Xiao-Ke Yang,Yan-Yan Liu,Wang-Dong Xu,Hai-Feng Pan,Dong-Qing Ye +8 more
TL;DR: It is summarized that Tyk2 is essential for the differentiation and function of a wide variety of immune cells, including natural killer cells, B cells, as well as T helper cells, and currently, structure-based drug design (SBDD) technology has provided a quite useful window for SBDD ofTyk2 inhibitors.
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Association of interleukin-1 receptor-associated kinase (IRAK1) gene polymorphisms (rs3027898, rs1059702) with systemic lupus erythematosus in a Chinese Han population.
TL;DR: The data demonstrate that the polymorphisms rs3027898 and rs1059702 of IRAK1 gene are associated with SLE in the Chinese Han population.
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Decreased serum level of IL-21 in new-onset systemic lupus erythematosus patients.
Hai-Feng Pan,Guo-Cui Wu,Yin-Guang Fan,Rui-Xue Leng,Hui Peng,Mo Zhou,Bao-Zhu Li,Yan Zhu,Jin-Hui Tao,Xiang-Pei Li,Dong-Qing Ye +10 more
TL;DR: Investigation of serum IL-21 levels in systemic lupus erythematosus (SLE) and its relations with clinical and laboratory features indicated a possible role of IL- 21 in human SLE, however, further studies are needed to confirm this preliminary results.
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