Yan Wang
7 Papers
Yan Wang is an academic researcher. The author has contributed to research in topics: Medicine & Inflammation. The author has an hindex of 1, co-authored 1 publications.
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Papers
Icariin and its metabolites as potential protective phytochemicals against cardiovascular disease: From effects to molecular mechanisms.
Yufei Zeng,Yilin Xiong,Tao Yang,Yan Wang,Jing Zeng,Shaoyu Zhou,Yunmei Luo,Lisheng Li +7 more
TL;DR: In this paper , the authors discuss the cardiovascular protective effects of icariin, an active component from Epimedium, and its metabolites, and summarize a range of studies showing that the modes of action on CVD relate to its inhibition of myocardial apoptosis and prevention of inflammation on endothelial cell injury.
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Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects
Wei Wei,Qingxuan Zeng,Yan Wang,Xixi Guo,Tian-Yun Fan,Ying-Hong Li,Hongbin Deng,Li-Ping Zhao,Xin–Tong Zhang,Yonghua Liu,Yulong Shi,Jin-tao Zhu,Xican Ma,Yan-Xiang Wang,Jiandong Jiang,Dan-Qing Song +15 more
TL;DR: Zhang et al. as discussed by the authors first identified EIF2AK2, eEF1A1, PRDX3 and VPS4B as direct targets of berberine (BBR) for its synergistically anti-inflammatory effects.
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The Protective Effects of Neoastilbin on Monosodium Urate Stimulated THP-1-Derived Macrophages and Gouty Arthritis in Mice through NF-κB and NLRP3 Inflammasome Pathways
TL;DR: Substantial evidence is provided for neoastilbin as a promising therapeutic agent for GA treatment by suppressing the activation of NF-κB and NLRP3 inflammasome pathways in both MSU stimulated THP-1-derived macrophages and the mouse model of GA.
Interleukin‑35 reduces inflammation in acute lung injury through inhibiting TLR4/NF‑κB signaling pathways
TL;DR: It is demonstrated that IL-35 may exhibit a protective role in ALI by modulating the TLR4/NF-κB signaling pathways.
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF- κ B/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury
TL;DR: The present study clarified the potential of EESD in the treatment of ALI and revealed its potential pharmacodynamic mechanism by inhibiting the NF-κB/NLRP3 inflammasome pathway and suppressing the pro-inflammatory phenotype activation of lung tissue macrophages.
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