Yan Sun
Shandong University
6 Papers
Yan Sun is an academic researcher from Shandong University. The author has contributed to research in topics: Kidney & Medicine. The author has an hindex of 6, co-authored 6 publications. Previous affiliations of Yan Sun include University of Sydney.
Chat about Author
Papers
IL-10/TGF-beta-modified macrophages induce regulatory T cells and protect against adriamycin nephrosis.
Qi Cao,Yiping Wang,Dong Zheng,Yan Sun,Ya Wang,Vincent W. Lee,Guoping Zheng,Thian Kui Tan,Jon Ince,Stephen I. Alexander,David Harris +10 more
TL;DR: It is demonstrated that IL-10/TGF-beta-modified macrophages effectively protect against renal injury in AN and may become part of a therapeutic strategy for chronic inflammatory disease.
260
Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease
Junyu Lu,Qi Cao,Dong Zheng,Yan Sun,Changqi Wang,Xiao Yu,Ya Wang,Vincent W. Lee,Guoping Zheng,Thian Kui Tan,Xin Wang,Stephen I. Alexander,David Harris,Yiping Wang +13 more
TL;DR: M(2c) are more potent than M(2a) macrophages in protecting against renal injury due to their ability to induce Tregs.
217
Sudan black B reduces autofluorescence in murine renal tissue.
TL;DR: This study demonstrates a simple, efficient, and cost-effective method to reduce autofluorescence using Sudan black B, and also provides a comprehensive approach to identify and minimize aut ofluorescence of renal tissue.
90
Transfused macrophages ameliorate pancreatic and renal injury in murine diabetes mellitus.
Dong Zheng,Yiping Wang,Qi Cao,Vincent W. Lee,Guoping Zheng,Yan Sun,Thian Kui Tan,Ya Wang,Stephen I. Alexander,David Harris +9 more
TL;DR: The findings show that M2 macrophages can protect against islet and renal injury in streptozotocin-induced diabetes, providing a potential therapeutic strategy for diabetes and diabetic nephropathy.
81
Failed renoprotection by alternatively activated bone marrow macrophages is due to a proliferation-dependent phenotype switch in vivo
Qi Cao,Yiping Wang,Dong Zheng,Yan Sun,Changqi Wang,Xin M. Wang,Vincent W. Lee,Ya Wang,Guoping Zheng,Thian Kui Tan,Yuan M. Wang,Stephen I. Alexander,David Harris +12 more
TL;DR: Bone marrow and splenic M2 macrophages showed similar regulatory phenotypes and suppressive functions in vitro as discussed by the authors, however, they did not improve renal function or reduce renal injury in adriamycin nephropathy.
70