6 Papers
11 Citations
Yan Sun is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Sirtuin 1 & AMPK. The author has an hindex of 5, co-authored 6 publications. Previous affiliations of Yan Sun include Nanjing University.
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Papers
Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium.
TL;DR: Astragaloside IV and cycloastragenol suppressed ROS-associated ER stress and then inhibited TXNIP/NLRP3 inflammasome activation with regulation of AMPK activity, and thereby ameliorated endothelial dysfunction by inhibiting inflammation and reducing cell apoptosis.
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Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1
TL;DR: Pharmacological activation of AMPK beneficially regulated adipocytokine expression in PVAT and thus ameliorated endothelial dysfunction against inflammatory insult in an AMPK/SIRT1-interdependent manner.
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Cyclocarya paliurus extract modulates adipokine expression and improves insulin sensitivity by inhibition of inflammation in mice.
Cuihua Jiang,Nan Yao,Qingqing Wang,Jinghua Zhang,Yan Sun,Na Xiao,Kang Liu,Fang Huang,Shengzuo Fang,Xulan Shang,Baolin Liu,Yicheng Ni,Zhi-Qi Yin,Jian Zhang +13 more
TL;DR: It is demonstrated that CPE beneficially regulated adipokines expression and ameliorated insulin resistance through inhibition of inflammation in mice.
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Quercetin, luteolin, and epigallocatechin gallate promote glucose disposal in adipocytes with regulation of AMP-activated kinase and/or sirtuin 1 activity.
Na Xiao,Na Xiao,Fan Mei,Fan Mei,Yan Sun,Yan Sun,Guojun Pan,Baolin Liu,Baolin Liu,Kang Liu,Kang Liu +10 more
TL;DR: Findings suggested that quercetin, luteolin, and epigallocatechin gallate inhibited inflammation and promoted glucose disposal in adipocytes with the regulation of AMP-activated kinase and/or sirtuin 1.
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Total polyphenol of Anemarrhena asphodeloides ameliorates advanced glycation end products-induced endothelial dysfunction by regulation of AMP-Kinase.
TL;DR: Wang et al. as mentioned in this paper investigated the effect of total polyphenol of Anemarrhena asphodeloides (TPAA) on endothelial dysfunction and to elucidate underlying mechanisms.
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