Yan Shi
Chinese Academy of Sciences
6 Papers
112 Citations
Yan Shi is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Gene & Gene expression. The author has an hindex of 6, co-authored 6 publications.
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Papers
The innate immune response to grass carp hemorrhagic virus (GCHV) in cultured Carassius auratus blastulae (CAB) cells.
TL;DR: Strong evidence is provided for existence of IFN antiviral innate immune response in fish, and the IFN response contributes to the formation of an antiviral state probably through JAK-STAT signaling pathway.
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Molecular characterization and subcellular localization of Carassius auratus interferon regulatory factor-1.
TL;DR: Subcellular localization analysis confirms the nuclear distribution of CaIRF-1 protein, and reveals two nuclear localization signals (NLS), any one of which is sufficient for nuclear translocation of Cairf-1, which is revealed as a new nuclear localization motif in the DBD of a vertebrate IRF- 1.
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Identification and characterization of interferon regulatory factor-1 from orange-spotted grouper (Epinephelus coioides).
TL;DR: Ex Expression analysis by real-time PCR reveals that the EcIRF-1 gene is ubiquitously expressed in various healthy fish tissues, whereas its expression is upregulated in vivo in response to polyinosinic–polycytidylic acid or lipopolysaccharide stimulation.
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Constitutive expression of thymidylate synthase from LCDV-C induces a transformed phenotype in fish cells
TL;DR: The data reveal LCDV-C TS is sufficient to induce a transformed phenotype in fish cells in vitro and exhibits its potential ability in cell transformation, the first report on viral TS sequences associated with transforming activity.
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Rana grylio virus thymidine kinase gene: an early gene of iridovirus encoding for a cytoplasmic protein
TL;DR: Current data indicate that RGV TK was an early gene of iridovirus which encoded a cytoplasmic protein in fish cells, which is much close to cellular TK type 2 (TK2), deoxycytidine kinase (dCK) and deoxyguanosine kinases (dGK).
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