Yan Luo
Sun Yat-sen University
74 Papers
299 Citations
Yan Luo is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Medicine & Retina. The author has an hindex of 24, co-authored 63 publications. Previous affiliations of Yan Luo include Yale University.
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Papers
Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis
Dianhong Luo,Yan Luo,Yun He,Haifeng Zhang,Rong Zhang,Xianghong Li,Wawrzyniec L. Dobrucki,Albert J. Sinusas,William C. Sessa,Wang Min +9 more
TL;DR: It is demonstrated that TNFR1 and TNFR2 play differential roles in ischemia-mediated arteriogenesis and angiogenesis, partly because of their opposite effects on EC survival and migration.
Endothelial-Specific Expression of Mitochondrial Thioredoxin Improves Endothelial Cell Function and Reduces Atherosclerotic Lesions
Haifeng Zhang,Yan Luo,Yan Luo,Wei Zhang,Wei Zhang,Yun He,Shengchuan Dai,Rong Zhang,Yan Huang,Pascal Bernatchez,Frank J. Giordano,Gerald S. Shadel,William C. Sessa,Wang Min +13 more
TL;DR: The role of the mitochondrial antioxidant system thioredoxin (Trx2) in vasculature is not understood by using endothelial cell (EC)-specific transgenesis of the mitochondria form of the thIoredoxin gene in mice (trx2 TG) as mentioned in this paper.
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Effects of culture conditions on heterogeneity and the apical junctional complex of the ARPE-19 cell line.
TL;DR: The properties of ARPE-19 appear to be changing in ways that may depend on how the cells are maintained and passaged, and this report examines its suitability for studying the tight junctions of the RPE.
124
•Journal Article
Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. Commentary
Parth Patwari,Richard T. Lee,Haifeng Zhang,Yan Luo,Wei Zhang,Yun He,Shengchuan Dai,Rong Zhang,Yan Huang,Pascal Bernatchez,Frank J. Giordano,Gerald S. Shadel,William C. Sessa,Wang Min +13 more
TL;DR: It is shown that Trx2 improves EC function and reduces atherosclerotic lesions in the apolipoprotein E-deficient mouse model and increases the capacities of ECs in scavenging reactive oxygen species generated from mitochondria, resulting in increases in NO bioavailability in ECs.
122
MicroRNA-26a and -26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway
Xiaoyun Chen,Wei Xiao,Weirong Chen,Xialin Liu,Mingxing Wu,Qu Bo,Yan Luo,Shaobi Ye,Yihai Cao,Yizhi Liu +9 more
TL;DR: In vitro and in vivo evidence is provided that Jagged-1/Notch signaling is activated in TGFβ2-stimulated EMT, and blockade of Notch signaling can reverse lens epithelial cells (LECs) EMT and lens fibrosis.