Yan Long
Peking University
23 Papers
7 Citations
Yan Long is an academic researcher from Peking University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 15 publications.
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Papers
Association between CYP2C19 and ABCB1 polymorphisms and clopidogrel resistance in clopidogrel-treated Chinese patients.
Zhong Ling Zhuo,Hai Peng Xian,Yan Long,Chang Liu,Yuan Yuan Sun,Yin Ting Ma,Hua Gao,Jing Zhong Zhao,Xiao Tao Zhao +8 more
TL;DR: The carriage of CYP2C19*2 or *3 mutant allele was significantly associated with attenuated platelet response to clopidogrel and increased CR risk.
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Increased circulating PD-1hiCXCR5- peripheral helper T cells are associated with disease severity of active ulcerative colitis patients.
TL;DR: In this paper, the authors investigated the changes of circulating peripheral helper T cells (Tph) in UC patients and their potential significance in the pathogenesis of UC and found that Tph levels were significantly positively correlated with Mayo score and serum CRP in active UC patients.
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Upregulated IL‐17A secretion and CCR6 co‐expression in Treg subsets are related to the imbalance of Treg/Th17 cells in active UC patients
TL;DR: It is suggested that upregulated IL‐17A secretion and CCR6 co‐expression in Treg subsets may be related to the imbalance between Tregs and Th17 cells and associated with the disease activity in UC patients.
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Recovery of CD226-TIGIT+FoxP3+ and CD226-TIGIT-FoxP3+ regulatory T cells contributes to clinical remission from active stage in ulcerative colitis patients.
TL;DR: Lack of CD226 expression on FoxP3+Tregs regardless of TIGIT expression may play an important role in exhibiting their suppressive function and preventing from disease activity in UC.
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Follicular Helper and Follicular Regulatory T Cell Subsets Imbalance is Associated with higher activated B cells and Abnormal Auto-antibody Production in Primary Anti-phospholipid Syndrome Patients
TL;DR: In this article, the authors investigated the role of Follicular helper T cells (Tfh) and Tfr in the pathogenesis of primary anti-phospholipid antibody syndrome (pAPS) and found that imbalance of circulating Tfr and Tfh, as well as their functional subsets, is associated with abnormal autoantibody levels in pAPS.
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