12 Papers
43 Citations
Yan Ling is an academic researcher from University of Southern Mississippi. The author has contributed to research in topics: Cluster (physics) & Density functional theory. The author has an hindex of 8, co-authored 12 publications. Previous affiliations of Yan Ling include Virginia Tech & University of Illinois at Urbana–Champaign.
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Papers
Bisphosphonate inhibitors of Toxoplasma gondi growth: in vitro, QSAR, and in vivo investigations.
Yan Ling,Gurmukh Sahota,Sarah Odeh,Julian M. W. Chan,Fausto G. Araujo,Silvia N.J. Moreno,Silvia N.J. Moreno,Eric Oldfield +7 more
TL;DR: The three most active compounds found in vitro were tested in vivo in a Smith-Webster mouse model and the two most active bisphosphonates were found to provide up to an 80% protection from death, a considerable improvement over that found previously with nitrogen-containing bisph phosphate compounds.
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The Farnesyl-diphosphate/Geranylgeranyl-diphosphate Synthase of Toxoplasma gondii Is a Bifunctional Enzyme and a Molecular Target of Bisphosphonates
TL;DR: The first bifunctional farnesyl-diphosphate/geranylgeranyl-dphosphate synthase identified in eukaryotes is reported, which establishes this enzyme as a valid target for the chemotherapy of toxoplasmosis.
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Preferential Encapsulation and Stability of La3N Cluster in 80 Atom Cages: Experimental Synthesis and Computational Investigation of La3N@C79N
Steven Stevenson,Yan Ling,Curtis Coumbe,Mary A. Mackey,Bridget S. Confait,J. Paige Phillips,Harry C. Dorn,Yong Zhang +7 more
TL;DR: To understand the geometric and electronic properties of this first metallic nitride azafullerene (M(3)N@C(79)N, M = La), density functional theory investigations were performed on a number of isomers and results suggest a dominant electronic effect on the stabilities of metalloazafullerenes.
Structural, EPR superhyperfine, and NMR hyperfine properties of the Cu-octarepeat binding site in the prion protein.
TL;DR: Results here suggest that the NMR hyperfine shifts which can be readily measured in NMR experiments and accurately predicted in quantum chemical calculations can provide more extensive and more sensitive structural probes than those from the current EPR studies.
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Metallic nitride azafullerenes: A novel class of fullerenes with interesting electronic properties
TL;DR: In this article, a quantum chemical investigation was reported on a series of MNAFs: LanSc3−nN@C79N, in which La and Sc represent the largest and smallest transition metals that can form stable endohedral metallofullerenes.
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