Yan Li
Bengbu Medical College
6 Papers
5 Citations
Yan Li is an academic researcher from Bengbu Medical College. The author has contributed to research in topics: Ischemia & Brain ischemia. The author has an hindex of 2, co-authored 5 publications.
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Papers
JAK2/STAT3 pathway is involved in the protective effects of epidermal growth factor receptor activation against cerebral ischemia/reperfusion injury in rats.
TL;DR: It is implicate that JAK2/STAT3 pathway plays the vital role in I/R injury protection from activating EGFR, and the neuroprotective effects may associate with inhibiting the Cx43 expression and the inhibition of apoptosis.
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Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy
TL;DR: It is suggested that EGCG could attenuate cardiac fibrosis in type 2 diabetic rats, and its underlying mechanisms associated with activation of autophagy via modulation of the AMPK/mTOR pathway and then repression of the TGF-β/MMPs pathway.
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[Protective effects of P2X7 receptor inhibition in cerebral ischemia/reperfusion injury in rats].
TL;DR: ERK inhibition is probably involved in the protective effects of P2X7R inhibitor against cerebral I/R injury, which may be related to the reduction of Cx43 and cleaved caspase-3, and the ratio of Bax/Bcl-2.
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•Journal Article
[Protective effect of propofol against cerebral ischemic/reperfusion injury may involve inhibition of gap junction].
TL;DR: The protective effect of propofol against cerebral I/R injury may involve the inhibition of the gap junction via PKC signaling and by reducing the Bax/Bcl-2 ratio.
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Impairment of spatial learning and memory and changes of oxidative stress in hippocampus from Type 1 diabetic mice
TL;DR: The established Type 1 diabetic mice show symptoms of cognitive dysfunction, which might be related to the increase of oxidative stress in hippocampus and the activity of iNOS and the content of MDA were markedly increased and theActivity of SOD was significantly decreased in hippocampus of diabetic encephalopathy mice.
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