Recently, using artificial intelligence (AI) in drug discovery has received much attention since it significantly shortens the time and cost of developing new drugs. Deep learning (DL)-based approaches are increasingly being used in all stages of drug development as DL technology advances, and drug-related data grows. Therefore, this paper presents a systematic Literature review (SLR) that integrates the recent DL technologies and applications in drug discovery Including, drug-target interactions (DTIs), drug-drug similarity interactions (DDIs), drug sensitivity and responsiveness, and drug-side effect predictions. We present a review of more than 300 articles between 2000 and 2022. The benchmark data sets, the databases, and the evaluation measures are also presented. In addition, this paper provides an overview of how explainable AI (XAI) supports drug discovery problems. The drug dosing optimization and success stories are discussed as well. Finally, digital twining (DT) and open issues are suggested as future research challenges for drug discovery problems. Challenges to be addressed, future research directions are identified, and an extensive bibliography is also included. 

/pdf/deep-learning-in-drug-discovery-an-integrative-review-and-2d4mceyl.pdf

Deep learning in drug discovery: an integrative review and future challenges

Artificial intelligence (AI) is an evolving set of technologies used for solving a wide range of applied issues. The core of AI is machine learning (ML)—a complex of algorithms and methods that address the problems of classification, clustering, and forecasting. The practical application of AI&ML holds promising prospects. Therefore, the researches in this area are intensive. However, the industrial applications of AI and its more intensive use in society are not widespread at the present time. The challenges of widespread AI applications need to be considered from both the AI (internal problems) and the societal (external problems) perspective. This consideration will identify the priority steps for more intensive practical application of AI technologies, their introduction, and involvement in industry and society. The article presents the identification and discussion of the challenges of the employment of AI technologies in the economy and society of resource-based countries. The systematization of AI&ML technologies is implemented based on publications in these areas. This systematization allows for the specification of the organizational, personnel, social and technological limitations. This paper outlines the directions of studies in AI and ML, which will allow us to overcome some of the limitations and achieve expansion of the scope of AI&ML applications.

/pdf/review-of-artificial-intelligence-and-machine-learning-e5ieghly.pdf

Review of Artificial Intelligence and Machine Learning Technologies: Classification, Restrictions, Opportunities and Challenges

Unmanned aerial vehicles (UAVs) are gaining considerable interest in transportation engineering in order to monitor and analyze traffic. This systematic review surveys the scientific contributions in the application of UAVs for civil engineering, especially those related to traffic monitoring. Following the PRISMA framework, 34 papers were identified in five scientific databases. First, this paper introduces previous works in this field. In addition, the selected papers were analyzed, and some conclusions were drawn to complement the findings. It can be stated that this is still a field in its infancy and that progress in advanced image processing techniques and technologies used in the construction of UAVs will lead to an explosion in the number of applications, which will result in increased benefits for society, reducing unpleasant situations, such as congestion and collisions in major urban centers of the world.

/pdf/urban-traffic-monitoring-and-analysis-using-unmanned-aerial-34italwd.pdf

Urban Traffic Monitoring and Analysis Using Unmanned Aerial Vehicles (UAVs): A Systematic Literature Review

The continual expansion of the range of applications for unmanned aerial vehicles (UAVs) is resulting in the development of more and more sophisticated systems. The greater the complexity of the UAV, the greater the likelihood that a component will fail. Due to the fact that drones often operate in close proximity to humans, the reliability of flying robots, which directly affects the level of safety, is becoming more important. This review article presents recent research works on fault detection on unmanned flying systems. They include papers published between January 2016 and August 2022. Web of Science and Google Scholar databases were used to search for articles. Terminology related to fault detection of unmanned aerial vehicles was used as keywords. The articles were analyzed, each paper was briefly summarized and the most important details concerning each of the described articles were summarized in the table.

/pdf/uav-fault-detection-methods-state-of-the-art-3fhyx8co.pdf

UAV Fault Detection Methods, State-of-the-Art

The use of unmanned aerial vehicles (UAVs) in various spheres of human activity is a promising direction for countries with very different types of economies. This statement refers to resource-rich economies as well. The peculiarities of such countries are associated with the dependence on resource prices since their economies present low diversification. Therefore, the employment of new technologies is one of the ways of increasing the sustainability of such economy development. In this context, the use of UAVs is a prospect direction, since they are relatively cheap, reliable, and their use does not require a high-tech background. The most common use of UAVs is associated with various types of monitoring tasks. In addition, UAVs can be used for organizing communication, search, cargo delivery, field processing, etc. Using additional elements of artificial intelligence (AI) together with UAVs helps to solve the problems in automatic or semi-automatic mode. Such UAV is named intelligent unmanned aerial vehicle technology (IUAVT), and its employment allows increasing the UAV-based technology efficiency. However, in order to adapt IUAVT in the sectors of economy, it is necessary to overcome a range of limitations. The research is devoted to the analysis of opportunities and obstacles to the adaptation of IUAVT in the economy. The possible economic effect is estimated for Kazakhstan as one of the resource-rich countries. The review consists of three main parts. The first part describes the IUAVT application areas and the tasks it can solve. The following areas of application are considered: precision agriculture, the hazardous geophysical processes monitoring, environmental pollution monitoring, exploration of minerals, wild animals monitoring, technical and engineering structures monitoring, and traffic monitoring. The economic potential is estimated by the areas of application of IUAVT in Kazakhstan. The second part contains the review of the technical, legal, and software-algorithmic limitations of IUAVT and modern approaches aimed at overcoming these limitations. The third part—discussion—comprises the consideration of the impact of these limitations and unsolved tasks of the IUAVT employment in the areas of activity under consideration, and assessment of the overall economic effect.

Review of Some Applications of Unmanned Aerial Vehicles Technology in the Resource-Rich Country

There are promising prospects on the way to widespread use of AI, as well as problems that need to be overcome to adapt AI&ML technologies in industries. The paper systematizes the AI sections and calculates the dynamics of changes in the number of scientific articles in machine learning sections according to Google Scholar. The method of data acquisition and calculation of dynamic indicators of changes in publication activity is described: growth rate (D1) and acceleration of growth (D2) of scientific publications. Analysis of publication activity, in particular, showed a high interest in modern transformer models, the development of datasets for some industries, and a sharp increase in interest in methods of explainable machine learning. Relatively small research domains are receiving increasing attention, as evidenced by the negative correlation between the number of articles and D1 and D2 scores. The results show that, despite the limitations of the method, it is possible to (1) identify fast-growing areas of research regardless of the number of articles, and (2) predict publication activity in the short term with satisfactory accuracy for practice (the average prediction error for the year ahead is 6%, with a standard deviation of 7%). This paper presents results for more than 400 search queries related to classified research areas and the application of machine learning models to industries. The proposed method evaluates the dynamics of growth and the decline of scientific domains associated with certain key terms. It does not require access to large bibliometric archives and allows to relatively quickly obtain quantitative estimates of dynamic indicators.

From Classical Machine Learning to Deep Neural Networks: A Simplified Scientometric Review

Based on statistics from the World Nuclear Association, Kazakhstan has the highest uranium production in the world. Most of the uranium in the country is mined via in-situ leaching and the accurate...

https://www.tandfonline.com/doi/pdf/10.1080/23311916.2020.1718821

One method of generating synthetic data to assess the upper limit of machine learning algorithms performance

Abstract The paper explores geophysical methods of wells survey, as well as their role in the development of Kazakhstan’s uranium deposit mining efforts. An analysis of the existing methods for solving the problem of interpreting geophysical data using machine learning in petroleum geophysics is made. The requirements and possible applications of machine learning methods in regard to uranium deposits of Kazakhstan are formulated in the paper.

/pdf/machine-learning-methods-for-identifying-composition-of-43ezjesd5r.pdf

Machine Learning Methods for Identifying Composition of Uranium Deposits in Kazakhstan

Project on creating a classifier of lithological types for uranium deposits in Kazakhstan

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