4 Papers
Yan He is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Radioresistance & PI3K/AKT/mTOR pathway. The author has an hindex of 4, co-authored 4 publications.
Chat about Author
Papers
Hypoxia-inducible factor 1α (HIF-1α) and reactive oxygen species (ROS) mediates radiation-induced invasiveness through the SDF-1α/CXCR4 pathway in non-small cell lung carcinoma cells
Qing Gu,Yan He,Jianfeng Ji,Yifan Yao,Wenhao Shen,Jia-Lin Luo,Wei Zhu,Han Cao,Yangyang Geng,Jing Xu,Shuyu Zhang,Jianping Cao,Wei Qun Ding +12 more
TL;DR: The findings have elucidated the underlying mechanisms of the irradiation-enhanced invasiveness of NSCLC cells and found that after irradiation, hypoxia-inducible factor 1α (HIF-1α) was increased and translocated into the nucleus, where it bound to the Hypoxia response element (HRE) in the CX CR4 promoter and promoted the transcription of CXCR4.
A Novel Role of Cab45-G in Mediating Cell Migration in Cancer Cells
Judong Luo,Zengpeng Li,Hong Zhu,Chenying Wang,Weibin Zheng,Yan He,Jianyuan Song,Wenjie Wang,Xifa Zhou,Xujing Lu,Shuyu Zhang,Jianming Chen +11 more
TL;DR: It is demonstrated that Cab 45-G exhibited an increased expression in cell lines with higher metastatic potential and promoted cell migration in multiple types of cancer cells, suggesting that Cab45-G could regulate cancer cell migration through various molecular mechanisms, which may serve as a therapeutic target for the treatment of cancers.
Radiation-induced miR-208a increases the proliferation and radioresistance by targeting p21 in human lung cancer cells
Yiting Tang,Yayun Cui,Zengpeng Li,Zhuqing Jiao,Yong Zhang,Yan He,Guangxia Chen,Qunyan Zhou,Wenjie Wang,Xifa Zhou,Judong Luo,Shuyu Zhang +11 more
TL;DR: Evidence is provided that miR-208a can affect the proliferation and radiosensitivity of human lung cancer cells by targeting p21 and can be transported by exosomes, which may serve as a potential therapeutic target for lung cancer patients.
Overexpression of Peroxiredoxin 6 (PRDX6) Promotes the Aggressive Phenotypes of Esophageal Squamous Cell Carcinoma.
Yan He,Wanglei Xu,Yuji Xiao,Lu Pan,Guangxia Chen,Yiting Tang,Jundong Zhou,Jinchang Wu,Wei Zhu,Shuyu Zhang,Jianping Cao +10 more
TL;DR: It is demonstrated that overexpression of PRDX6 promotes the progression of ESCC through Erk1/2, which provides a potential therapeutic target for human ESCC.