19 Papers
Yan E is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 5 publications.
Chat about Author
Papers
ACE2 activator diminazene aceturate ameliorates Alzheimer's disease-like neuropathology and rescues cognitive impairment in SAMP8 mice
Rui Duan,Xiao Xue,Qiao-Quan Zhang,Si-Yu Wang,Pengyu Gong,Yan E,Teng Jiang,Ying-Dong Zhang,Ying-Dong Zhang +8 more
- 23 Jul 2020
TL;DR: It is demonstrated that DIZE ameliorates AD-like neuropathology and rescues cognitive impairment in SAMP8 mice and highlights brain ACE2/Ang-(1-7)/MAS1 axis as a potential target for the treatment of sporadic AD.
41
The Role of TREML2 in Alzheimer's Disease.
TL;DR: The latest findings regarding cellular localization and biological functions of TREML2 are summarized and its possible role in AD pathogenesis is speculated.
13
A TREML2 missense variant influences specific hippocampal subfield volumes in cognitively normal elderly subjects.
TL;DR: To uncover the possible mechanisms by which TREML2 rs3747742‐C reduces AD risk, the possible relation of this variant with AD‐related brain structures using a cognitively normal elderly population from ADNI database is investigated.
11
Bilirubin Improves Gap Junction to Alleviate Doxorubicin-Induced Cardiotoxicity by Regulating AMPK-Axl-SOCS3-Cx43 Axis
Siqi Zhang,Binbin Zheng,Yu Wang,Chengkui Miao,Yue Su,Kun-Yi Li,Yan E,Xueli Wang,Xue-Zhi He,Xudong Wu,Chen-Jie Xu,Yu-Lin Tang,Wen-Tao Liu,Xiangqing Kong,Liangao Hu +14 more
TL;DR: Bilirubin upregulates gap junctions’ function to protect against doxorubicin-induced cardiotoxicity by activating AMPK-Axl-SOCS3 signaling axis and provides theoretical support for drug development.
Hypersensitive C-reactive protein-albumin ratio predicts symptomatic intracranial hemorrhage after endovascular therapy in acute ischemic stroke patients
Qiang Peng,Jian-Kang Hou,Si-Yu Wang,Feng Zhou,Yan E,Wei Wang,Ting Huang,Meng Wang,Shi Huang,Junshan Zhou,Nihong Chen,Ying-Dong Zhang +11 more
TL;DR: Univariate logistic regression analysis demonstrated that patients with higher levels of hypersensitive C-reactive protein-albumin ratio may be inclined to develop symptomatic intracranial hemorrhage (sICH) after endovascular therapy.