Ya-Xing Shen
Fudan University
6 Papers
1 Citations
Ya-Xing Shen is an academic researcher from Fudan University. The author has contributed to research in topics: Gene silencing & Metastasis. The author has an hindex of 2, co-authored 2 publications.
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Papers
CircBCAR3 accelerates esophageal cancer tumorigenesis and metastasis via sponging miR-27a-3p
Yong Xi,Ya-Xing Shen,Dong-Ning Wu,Jingtao Zhang,Chengbin Lin,Lijie Wang,Chaoqun Yu,Bentong Yu,Weiyu Shen +8 more
TL;DR: In this paper , the authors investigated the oncogenic roles and biogenesis of circBCAR3 in esophageal carcinogenesis using loss-of-function assays and showed that splicing factor quaking (QKI) is a positive regulator of circRNAs via targeting the introns flanking the hsa_circ_0007624-formed exons in BCAR3 premRNA.
CircBCAR3 accelerates esophageal cancer tumorigenesis and metastasis via sponging miR-27a-3p
Yong Xi,Ya-Xing Shen,Dong-Ning Wu,Jingtao Zhang,Chengbin Lin,Lijie Wang,Chaoqun Yu,Bentong Yu,Weiyu Shen +8 more
TL;DR: In this article , the authors investigated the oncogenic roles and biogenesis of circBCAR3 in esophageal carcinogenesis using loss-of-function assays and showed that splicing factor quaking (QKI) is a positive regulator of circRNAs via targeting the introns flanking the hsa_circ_0007624-formed exons in BCAR3 premRNA.
Expression and prognostic roles of TRPV5 and TRPV6 in non-small cell lung cancer after curative resection.
TL;DR: Investigation of the expression of epithelial Ca2+ channel transient receptor potential vanilloid (TRPV) 5 and 6 in non-small-cell lung cancer and their prognostic role in patients after surgical resection found decreased expression in tumor tissues was observed in NSCLC patients and was associated with shorter median survival time.
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circPOLR1C Promotes the Development of Esophageal Cancer by Adsorbing miR-361-3p and Regulating Cancer Cell Apoptosis and Metastasis
TL;DR: In this paper , the effect and regulatory mechanism of circPOLR1C on esophageal cancer (EC) was revealed by qRT-PCR, RNase R, actinomycin D, and fluorescence in situ hybridization (FISH) assay.
miR-140 suppresses tumor growth and metastasis of non-small cell lung cancer by targeting insulin-like growth factor 1 receptor.
TL;DR: It is found that miR-140 is significantly downregulated in NSCLC tissues and cell lines, and overexpression of IGF1R attenuated the function of miR -140 inNSCLC cells.