Ya Ru Yan
Shanghai Jiao Tong University
17 Papers
9 Citations
Ya Ru Yan is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Obstructive sleep apnea & Medicine. The author has an hindex of 3, co-authored 9 publications.
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Papers
Chronic intermittent hypoxia-induced mitochondrial dysfunction mediates endothelial injury via the TXNIP/NLRP3/IL-1β signaling pathway
Ya Ru Yan,Liu Zhang,Ying Ni Lin,Xian Wen Sun,Yong Jie Ding,Ning Li,Hong Peng Li,Shi Qi Li,Jian Ping Zhou,Qing Yun Li +9 more
TL;DR: In this article, the authors investigated the role of chronic intermittent hypoxia (CIH) induced mitochondrial dysfunction in vascular endothelial injury both in vivo and in vitro and found that the NOD-like receptor signaling pathway was involved in endothelial injuries induced by CIH, and showed that mito-TEMPO improved mitochondrial function and suppressed upregulation of the TXNIP/NLRP3/IL-1β pathway.
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The Role of Aldosterone in OSA and OSA-Related Hypertension
Yi Wang,Chuan Xiang Li,Ying Ni Lin,Li Zhang,Shi Qi Li,Liu Zhang,Ya Ru Yan,Fang-Ying Lu,Ning Li,Qing Yun Li +9 more
TL;DR: A bidirectional influence between OSA and aldosterone exists and contributes to hypertension in OSA patients, especially resistant hypertension.
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Impact of insomnia and obstructive sleep apnea on the risk of acute exacerbation of chronic obstructive pulmonary disease.
Shi Qi Li,Xian Wen Sun,Liu Zhang,Yong Jie Ding,Hong Peng Li,Ya Ru Yan,Ying Ni Lin,Jian Ping Zhou,Qing Yun Li +8 more
TL;DR: In this paper, sleep disorders are considered in clinical management for chronic obstructive pulmonary disease (COPD), and effective continuous positive airway pressure (CPAP) treatment may reduce the risk of AECOPD and mortality in patients with overlap syndrome.
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Relationship between monocyte to HDL cholesterol ratio and concomitant cardiovascular disease in Chinese Han patients with obstructive sleep apnea.
TL;DR: MHR is strongly correlated with the severity of OSA and the occurrence of CVD in OSA patients, and is expected to be a promising biomarker candidate in predictingCVD in Chinese Han patients with OSA.
The Association of Salivary Biomarkers With the Severity of Obstructive Sleep Apnea and Concomitant Hypertension.
TL;DR: Salivary alpha-amylase is positively associated with the severity of OSA and OSA concomitant hypertension.
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