4 Papers
Ya Fu is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Diacylglycerol kinase & Caenorhabditis elegans. The author has an hindex of 4, co-authored 4 publications.
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Papers
Protein kinase D: coupling extracellular stimuli to the regulation of cell physiology
Ya Fu,Charles S. Rubin +1 more
TL;DR: Selective PKD inhibitors provide new, powerful tools for elucidating the physiological roles of PKDs and potentially treating cardiac disease and cancer.
Neuronal and Intestinal Protein Kinase D Isoforms Mediate Na+ (Salt Taste)–Induced Learning
TL;DR: It is shown that pathways containing EGL-8–TPA-1–DKF-2 enable learning and behavioral plasticity by receiving, transmitting, and cooperatively integrating environmental signals targeted to both neurons and intestine.
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Protein Kinase D Is an Essential Regulator of C. elegans Innate Immunity
TL;DR: It is shown that DKF-2, a C. elegans PKD, regulates innate immunity and provides a molecular link that couples DAG signaling to regulation of immunity and mobilizes activation of host immune defenses against pathogens by previously unappreciated signaling pathways and mechanisms.
A RasGRP, C. elegans RGEF-1b, Couples External Stimuli to Behavior by Activating LET-60 (Ras) in Sensory Neurons
TL;DR: Diacylglycerol-activated RGEF-1b links external stimuli (odorants) to behavior (chemotaxis) by activating the LET-60-MPK-1 pathway in specific neurons and was essential for sensory signaling in vivo.