Ya-Chen Lin
Vanderbilt University Medical Center
13 Papers
6 Citations
Ya-Chen Lin is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Parkinson's disease & Medicine. The author has an hindex of 7, co-authored 13 publications.
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Papers
Nigrostriatal and Mesolimbic D2/3 Receptor Expression in Parkinson's Disease Patients with Compulsive Reward-Driven Behaviors.
Adam J. Stark,Christopher T. Smith,Ya-Chen Lin,Kalen J. Petersen,Paula Trujillo,Nelleke C. van Wouwe,Hakmook Kang,Manus J. Donahue,Robert M. Kessler,David H. Zald,David H. Zald,Daniel O. Claassen +11 more
TL;DR: The hypothesis that compulsive behaviors in PD are associated with reduced ventral and dorsal striatal D2/3 expression, similar to changes in comparable behavioral disorders is supported.
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Quantitative magnetization transfer imaging of the human locus coeruleus
Paula Trujillo,Kalen J. Petersen,Matthew J. Cronin,Ya-Chen Lin,Hakmook Kang,Manus J. Donahue,Seth A. Smith,Daniel O. Claassen +7 more
TL;DR: The role of MT in generating NM-related contrast in the LC is highlighted by applying high spatial resolution quantitative MT (qMT) imaging to create parametric maps of the macromolecular content of the LC and surrounding tissues.
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Dopamine effects on frontal cortical blood flow and motor inhibition in Parkinson's disease
Paula Trujillo,Nelleke C. van Wouwe,Ya-Chen Lin,Adam J. Stark,Kalen J. Petersen,Hakmook Kang,David H. Zald,Manus J. Donahue,Daniel O. Claassen +8 more
TL;DR: It is shown that dopamine agonist administration increases frontal cerebral blood flow, particularly in the pre-supplementary motor area (pre-SMA) and the dorsolateral prefrontal cortex (DLPFC), suggesting that treatments which improve frontal cortical activity could ameliorate motor inhibition deficiency in PD patients.
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Structural Correlates of the Sensorimotor Cerebellum in Parkinson's Disease and Essential Tremor
Alexander M Lopez,Paula Trujillo,Adreanna B Hernandez,Ya-Chen Lin,Hakmook Kang,Bennett A. Landman,Dario J. Englot,Benoit M. Dawant,Peter E. Konrad,Daniel O. Claassen +9 more
TL;DR: There are limited studies investigating cerebellar structural changes in Parkinson's disease and essential tremor, largely because of inherent challenges in the efficiency of segmentation.
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Empowering the Clinical Research Coordinator in Academic Medical Centers
Danielle A. Buchanan,Jody Goldstein,Anna C Pfalzer,Ya-Chen Lin,Hakmook Kang,Daniel O. Claassen +5 more
TL;DR: Surprisingly, greater workload and lack of opportunity for professional growth were not associated with retention and the CRCs who feel respected and engaged by the PI and are adequately compensated are more likely to have higher job satisfaction and retention.
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