Ya Chen
Guiyang Medical University
1 Papers
1 Citations
Ya Chen is an academic researcher from Guiyang Medical University. The author has contributed to research in topics: Bile acid & Adefovir. The author has an hindex of 1, co-authored 1 publications.
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Papers
Novel adefovir mono L-amino acid ester, mono bile acid ester derivatives: Design, synthesis, biological evaluation, and molecular docking study
Ya Chen,Wen Zheng Zhang,Jing Li,Tao Xiao,Jiang Xia Liu,Min Luo,Hang Su,Xiao-Zhong Fu,Ting Liu,Yong-Xi Dong,Yong-Long Zhao,Bin He,Yongjun Li +12 more
TL;DR: A series of adefovir mono L-aminoacid ester, mono bile acid ester derivatives have potent anti-anti-hepatitis B activity, especially compound 6c, which has more potent antiviral activity and a higher selectivity index (EC50 0.65 μmol/L, SI 582).
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