Y. Sommerer
11 Papers
2 Citations
Y. Sommerer is an academic researcher. The author has contributed to research in topics: Medicine & Epigenetics. The author has an hindex of 2, co-authored 8 publications.
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Papers
DNA methylation age acceleration is associated with risk of diabetes complications
Valentin Max Vetter,Johanne Spieker,Y. Sommerer,Nikolaus Buchmann,C. Kalies,Vera Regitz-Zagrosek,Lars Bertram,Ilja Demuth +7 more
TL;DR: In this paper , the authors examined older adults of the Berlin Aging Study II that were reexamined on average 7.4 years after baseline assessment as part of the GendAge study.
Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates
Lars Nyberg,Micael Andersson,Anders Lundquist,William F. C. Baaré,David Bartrés-Faz,Lars Bertram,Carl-Johan Boraxbekk,Andreas M. Brandmaier,Naiara Demnitz,Christian A. Drevon,Sandra Duezel,Klaus P. Ebmeier,Paolo Ghisletta,Richard N. Henson,Daria E. A. Jensen,Rogier A. Kievit,Ethan Knights,Simone Kühn,Ulman Lindenberger,Anna Plachti,Sara Pudas,James M Roe,Kathrine Skak Madsen,Cristina Solé-Padullés,Y. Sommerer,Sana Suri,Enikő Zsoldos,Anders M. Fjell,Kristine B. Walhovd +28 more
TL;DR: The results supported a 2-group solution reflecting differences in atrophy rates in cortical regions and hippocampus along with comparable caudate atrophy and suggest distinct mechanisms of atrophy in striatal versus hippocampal-cortical systems.
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Epigenetic aging and perceived psychological stress in old age
Valentin Max Vetter,Johanna Drewelies,Y. Sommerer,C. Kalies,Vera Regitz-Zagrosek,Lars Bertram,Denis Gerstorf,Ilja Demuth +7 more
TL;DR: For instance, the authors found no evidence for an association of perceived stress with DNA methylation age acceleration (DNAmAA) in older adults, and they did not find any statistically significant association of stress with any of the five epigenetic clocks in multiple linear regression analyses.
Epigenome-Wide Association Study in Peripheral Tissues Highlights DNA Methylation Profiles Associated with Episodic Memory Performance in Humans
Y. Sommerer,Valerija Dobricic,Marcel Schilling,Olena Ohlei,David Bartrés-Faz,Gabriele Cattaneo,Ilja Demuth,Sandra Düzel,Sören Franzenburg,Janina Fuss,Ulman Lindenberger,Alvaro Pascual-Leone,Sanaz Sedghpour Sabet,Cristina Solé-Padullés,José María Tormos,Valentin Max Vetter,Tanja Wesse,Andre Franke,Christina M. Lill,Lars Bertram +19 more
TL;DR: The authors conducted an epigenome-wide association study (EWAS) using DNA methylation (DNAm) profiles from buccal and blood samples for cross-sectional and longitudinal changes in episodic memory performance (n = 626; average follow-up time 5.4 years).
DNA Methylation Age Acceleration, Type 2 Diabetes, and its Complications: Cross-Sectional and Longitudinal Data from the Berlin Aging Study II (BASE-II)
Valentin Max Vetter,Janine Spieker,Y. Sommerer,Nikolaus Buchmann,C. Kalies,Vera Regitz-Zagrosek,Lars Bertram,Ilja Demuth +7 more
TL;DR: Although the findings still need to be independently validated, the 7-CpG clock appears to be a promising biomarker which is informative about the individual risk for diabetic complications independent of age, sex, lifestyle factors, or complications at baseline.
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