Y. Kashiwabara
Cornell University
2 Papers
73 Citations
Y. Kashiwabara is an academic researcher from Cornell University. The author has contributed to research in topics: Nitric oxide synthase & Binding site. The author has an hindex of 2, co-authored 2 publications.
Chat about Author
Papers
Carboxyl terminus of inducible nitric oxide synthase. Contribution to NADPH binding and enzymatic activity.
Qiao-wen Xie,Hearn Cho,Y. Kashiwabara,M. Baum,J. R. Weidner,Keith O. Elliston,R. Mumford,Carl Nathan +7 more
TL;DR: It is demonstrated that the carboxyl terminus of NOS is a functionally critical region, and the short form NOS lacks NOS activity.
76
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.
TL;DR: Reporter constructs containing truncated promoter regions revealed that activation of NF-kappa B/Rel is critical in the induction of iNOS by LPS, however, additional, newly synthesized proteins contribute to the NF- kappa Bd-dependent transcription factor complex on the iN OS promoter in LPS-treated mouse macrophages.