Xun-Cui Wang
Anhui University
19 Papers
24 Citations
Xun-Cui Wang is an academic researcher from Anhui University. The author has contributed to research in topics: Chemistry & Apoptosis. The author has an hindex of 7, co-authored 9 publications. Previous affiliations of Xun-Cui Wang include Anhui University of Chinese Medicine.
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Papers
Involvement of ubiquitin proteasome system in protective mechanisms of Puerarin to MPP+-elicited apoptosis
Yue-Fa Cheng,Guo-Qi Zhu,Mei Wang,Hui Cheng,An Zhou,Ning Wang,Nianbai Fang,Xun-Cui Wang,Xiao-Qiu Xiao,Zhi-Wu Chen,Qinglin Li +10 more
TL;DR: Perarin could protect MPP(+)-induced SH-SY5Y cells from apoptosis by regulating the function of UPS, as evidenced by promoting cell viability, improving morphological changes and reducing apoptotic rate.
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Polysaccharides from Polygonatum cyrtonema Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis
TL;DR: In this paper , the effects of polygonatum cyrtonema Hua polysaccharide (PSP) on depression were investigated in the presence of mild stress and chronic unpredictable mild stress induced depression.
Synthesis and Evaluation of Paeonol Derivatives as Potential Multifunctional Agents for the Treatment of Alzheimer’s Disease
TL;DR: Paeonol derivatives 5a–5d may be promising multifunctional agents for AD treatment and could significantly inhibit hydrogen peroxide-induced neuronal PC12 cell death assessed by MTT assay in the concentration range of 5–40 μM.
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Paeonol prevents excitotoxicity in rat pheochromocytoma PC12 cells via downregulation of ERK activation and inhibition of apoptosis.
TL;DR: The data suggest that paeonol develops its neuroprotective effect against glutamate neurotoxicity through inhibition of the apoptotic signaling pathway and upregulation of the p-ERK pathway.
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Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice: Mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation.
Pan Xie,Lixia Chen,Juan Wang,Xun-Cui Wang,Shaojie Yang,Guoqi Zhu +5 more
TL;DR: Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice by regulating synaptic injury, oxidative stress, and neuroinflammation, likely through the Nrf2/HO-1 signaling pathway, and inhibiting NLRP3-mediated inflammation.
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