Xuetao Cao
Peking Union Medical College
537 Papers
5.2K Citations
Xuetao Cao is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Immune system & Biology. The author has an hindex of 95, co-authored 509 publications. Previous affiliations of Xuetao Cao include Transgene SA & Huazhong University of Science and Technology.
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Papers
Effective induction of therapeutic antitumor immunity by dendritic cells coexpressing interleukin-18 and tumor antigen
Dajing Xia,Shu Zheng,Weiping Zhang,Long He,Qingqing Wang,Jianping Pan,Lihuang Zhang,Jianli Wang,Xuetao Cao,Xuetao Cao +9 more
TL;DR: Results indicate that immunization with DC vaccine coexpressing Th1 cytokine IL-18 and tumor antigen gene may be an effective strategy for a successful therapeutic vaccination.
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Highlights of the advances in basic immunology in 2011.
TL;DR: This review summarizes the major fundamental advances in immunological research reported in 2011 and focuses on the improved understanding of key questions in basic immunology, including the initiation and activation of innate responses as well as mechanisms for the development and function of various T-cell subsets.
Potent antitumor effect elicited by superantigen-linked tumor cells transduced with heat shock protein 70 gene.
Changxin Huang,Hai Yu,Qingqing Wang,Wenxue Ma,Dajing Xia,Ping-Yong Yi,Lihuang Zhang,Xuetao Cao +7 more
TL;DR: The results indicated that the dual‐modified vaccine could induce a potent tumor‐antigen‐specific immune response in addition to an increase of non‐specific immunity.
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Protein Tyrosine Phosphatase with Proline-Glutamine-Serine-Threonine–Rich Motifs Negatively Regulates TLR-Triggered Innate Responses by Selectively Inhibiting IκB Kinase β/NF-κB Activation
TL;DR: PTP-PEST functions as a feedback-negative regulator of TLR-triggered innate immune responses by selectively impairing IKK β/NF-κB activation and suppressing IKKβ activation and kinase activity as well as downstream NF-κBs activation.
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Dicer-independent snRNA/snoRNA-derived nuclear RNA 3 regulates tumor-associated macrophage function by epigenetically repressing inducible nitric oxide synthase transcription.
TL;DR: In this paper, a new class of nucleus-localized small RNAs, named snRNA/snoRNA-derived nuclear RNAs (sdnRNAs), were identified, which were enriched in the nucleus and investigated their function in mediating gene-specific epigenetic regulation in anti-tumor immunity.