Various etiologies could cause focal I accumulation. Hepatic cyst is one of these etiologies. Here we present a 59-year-old man with a history of papillary thyroid cancer resection who received radioiodine therapy for three times. The images after the I therapy of the second and third time showed variable activity uptake in the same hepatic cysts.

Variable 131I Activity in Multiple Hepatic Cysts in a Patient With Thyroid Cancer.

Incidentally polycystic kidney disease identified by SPECT/CT with post-therapy radioiodine scintigraphy in a patient with differentiated thyroid carcinoma: A case report

The adrenal metastasis from differentiated thyroid carcinoma is uncommon. Metastatic involvement of both adrenal and brain in the same patient from differentiated thyroid carcinoma is rare. Here, we described an unusual case with iodine-avid lung, bone, adrenal, liver, and brain metastases from follicular thyroid carcinoma confirmed by 131I SPECT/CT. The utilization of SPECT/CT in thyroid cancer patients can detect the presence of metastases and also exclude potential false-positive lesions. Our case demonstrates that SPECT/CT is helpful in localizing and confirming metastatic lesions from differentiated thyroid carcinoma in rare and unusual sites.

Unusual Adrenal and Brain Metastases From Follicular Thyroid Carcinoma Revealed by 131I SPECT/CT.

Radioactive iodine ablation has long-lasting effects on remnant thyroid tissue and metastasis from well-differentiated thyroid cancer. After radioactive iodine treatment, scintigraphy is a major imaging modality for detecting metastasis and assessing its management. False-positive iodine uptake can be found in many aberrant locations, including cysts. This report describes iodine uptake in retroperitoneal cysts in a 62-year-old woman diagnosed with papillary thyroid carcinoma. Radioiodine scintigraphy was performed after iodine therapy. Abnormally increased iodine activity was noted in the left upper abdomen. Additional radiologic examinations helped in preventing invasive biopsy.

Iodine Uptake in Retroperitoneal Cysts after Radioactive Iodine Treatment.

Interpretation of iodine 131I whole-body scintigraphy can be challenging, as there are many nonpathologic findings that may present with increased radiotracer uptake. Radiotracer uptake has been reported in the literature involving the salivary glands, thymus, renal cysts, skin contamination

Ganglion Cyst on 131I Whole-Body Scintigraphy.

Nasal iodine activity can be observed on 123Iodine (123I) or 131I whole-body scintigraphy (WBS) commonly as a normal variant caused by nasal or salivary secretion of the tracer. We encountered 2 patients whose increased accumulation of 131I activity was associated with underlying abnormalities. One patient had a nasal polyp, whereas the other had an abscess.

Nasal visualization on radioiodine whole-body scintigraphy due to benign abnormality

High-dose palliative radiotherapy in metastatic castrate resistant prostate cancer – is it worthwhile? A single-centre outcome

The incidence of retroperitoneal bronchial cyst is rare and is unusual to be visualized on I scan. We report a 52-year-old man who received I therapy for papillary thyroid cancer. The postablation whole-body scan revealed increased radioiodine activity in the left abdomen. SPECT/CT localized this activity from a soft tissue mass in the retroperitoneal space. A retroperitoneal tumor was considered, and retroperitoneal laparoscopic tumor resection was performed. Pathologic examination confirmed a retroperitoneal bronchogenic cyst.

Unusual uptake of radioiodine in a retroperitoneal bronchogenic cyst in a patient with thyroid carcinoma.

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Papers

Nasal visualization on radioiodine whole-body scintigraphy due to benign abnormality

High-dose palliative radiotherapy in metastatic castrate resistant prostate cancer – is it worthwhile? A single-centre outcome

Unusual uptake of radioiodine in a retroperitoneal bronchogenic cyst in a patient with thyroid carcinoma.