Xue Ding
7 Papers
Xue Ding is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 6 publications.
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Papers
KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron-responsive element-binding protein 2
Hui-Jun Zhou,Junru Chen,Mingjie Fan,Huajian Cai,Yufei Dong,Yue Qiu,Qianqian Zhuang,Zhaoying Lei,Mengyao Li,Xue Ding,Peng Yan,Aifu Lin,Shusen Zheng,Qingfeng Yan +13 more
TL;DR: In this article , the authors found fluphenazine is an activator of Krüpple-like factors (KLF) in hepatocellular carcinoma (HCC) cells, which inhibited HCC cells growth through inducing iron deficiency.
The significance of the crosstalk between ubiquitination or deubiquitination and ncRNAs in non-small cell lung cancer
TL;DR: In this article , the authors presented several typical examples of the important effects of ncRNAs and ubiquitination (or deubiquitination) in lung cancer, aiming to provide more creative ideas for exploring the diagnosis and treatment of NSCLC.
Impaired AIF-CHCHD4 interaction and mitochondrial calcium overload contribute to auditory neuropathy spectrum disorder in patient-iPSC-derived neurons with AIFM1 variant
Yue Qiu,Hongyang Wang,Mingjie Fan,Huaye Pan,Jing Guan,Yangwei Jiang,Zexiao Jia,Kaiwen Wu,Hui Zhou,Qianqian Zhuang,Zhaoying Lei,Xue Ding,Huajian Cai,Yufei Dong,Le-Qin Yan,Aifu Lin,Yong Fu,Dong Xing Zhang,Qingfeng Yan,Qiuju Wang +19 more
TL;DR: In this article , the authors demonstrated that the AIFM1 variant is one of the molecular bases of auditory neuropathy spectrum disorder (ANSD) and showed that correction of this variant significantly restored the structure and function of AIF, further improving the physiological state of patient-specific iPSC-derived neurons.
Novel DNJ Derivative Ameliorates Cardiac Hypertrophy by Targeting OPA1 and Restoring Mitochondrial Health.
Xue Ding,Yangwei Jiang,Xiaochen Wang,Chujun Li,Zhengyi Kong,Lei Fu,Zhaoying Lei,Huajian Cai,Yufei Dong,Chengyu Shi,Xinwan Su,Tilo Kunath,Ziyi Wang,D. Buratto,Ai-fu Lin,Jianzhong Shao,Dong Xing Zhang,Zhong Liu,Ping Liang,Ruhong Zhou,Qingfeng Yan +20 more
TL;DR: Researchers design and identify a novel DNJ derivative, DNJ5a, that targets OPA1 and restores mitochondrial health, effectively ameliorating cardiac hypertrophy in rodent models through improved bioenergetics, Ca2+ homeostasis, and mitophagy.
1-Deoxynojirimycin promotes cardiac function and rescues mitochondrial cristae in mitochondrial hypertrophic cardiomyopathy
Qianqian Zhuang,Fengfeng Guo,Yufei Dong,Shaofang Xie,Xue Ding,Shuang-yi Hu,Xuanhao Zhou,Yangwei Jiang,Hui Zhou,Yue Qiu,Zhaoying Lei,Mengyao Li,Huajian Cai,Mingjie Fan,Ling Sang,Yong Fu,Dong Xing Zhang,Aifu Lin,Xu Li,Tilo Kunath,Ruhong Zhou,Ping Liang,Zhong Liu,Qingfeng Yan +23 more
TL;DR: In this article , 1-Deoxynojirimycin (DNJ) was identified to rescue mitochondrial function by targeting optic atrophy protein 1 (OPA1) to promote its oligomerization, leading to reconstruction of the mitochondrial cristae.