Xinyue Lian
Shanghai Jiao Tong University
7 Papers
Xinyue Lian is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Medicine & Fermentation. The author has an hindex of 3, co-authored 3 publications.
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Papers
Mortality Risk Prediction in Amyopathic Dermatomyositis Associated With Interstitial Lung Disease: The FLAIR Model.
Xinyue Lian,Jing Zou,Qiang Guo,Sheng Chen,Liangjing Lu,Ran Wang,Mengmeng Zhou,Qiong Fu,Yan Ye,Chunde Bao +9 more
TL;DR: The FLAIR risk score model could help predict survival in ADM-ILD patients and guide further clinical research on risk-based treatment.
99
Prognostic values of anti-Ro52 antibodies in anti-MDA5-positive clinically amyopathic dermatomyositis associated with interstitial lung disease
Antao Xu,Yan Ye,Qiong Fu,Xinyue Lian,Sheng Chen,Qiang Guo,Liangjing Lu,Min Dai,Xia Lv,Chunde Bao +9 more
TL;DR: Anti-Ro52 antibody is highly prevalent in anti-MDA5-positive CADM-ILD patients and their coexistence correlates with a subgroup of patients with more aggressive phenotypes, which could help to predict patients' prognosis and guide risk-based therapy.
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Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications
Yan Ye,Zechuan Chen,Shan Jiang,Fengyun Jia,Teng Li,Jing Xue,Xinyue Lian,Jiaqiang Ma,Pei Hao,Liangjing Lu,Shuang Ye,Nan Shen,Chunde Bao,Qiong Fu,Xiaoming Zhang +14 more
TL;DR: In this paper , the authors describe the immune signatures of MDA5+ DM via single-cell RNA sequencing, flow cytometry and multiplex immunohistochemistry in peripheral B and T cells and in affected lung tissue samples from one patient.
Longitudinal study of patients with antimelanoma differentiation-associated gene 5 antibody-positive dermatomyositis associated interstitial lung disease.
Xinyue Lian,Yan Ye,Jing Zou,Chunmei Wu,Shuang Ye,Qiang Guo,Sheng Chen,Liangjing Lu,Ran Wang,Qiong Fu,Chunde Bao +10 more
TL;DR: MDA5+ DM-ILD patients had a high mortality rate despite aggressive treatment and patients who survived the first year usually showed a significant improvement in serological markers and pulmonary function during the long-term follow-up.
5
Analysis of Metabolic Differences in the Water Extract of Shenheling Fermented by Lactobacillus fermentum Based on Nontargeted Metabolomics
Xiantao Yan,Min Liu,Congcong Guo,Xinyue Lian,Yun Shen,Yang Liu,Yi Qian,Longfei Zhang,Wenqiong Wang,Dawei Chen,Jianya Qian,Ruixia Gu +11 more
TL;DR: In this article , the characteristics of metabolites in Shenheling (SHL) fermented by Lactobacillus fermentum were explored using ultrahigh-performance liquid chromatography-quadrupole electrostatic field orbit trap mass spectrometry (UHPLC-QE-MS).