Xinyuan Ding
Nanjing Medical University
4 Papers
Xinyuan Ding is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Neural stem cell & Wnt signaling pathway. The author has an hindex of 2, co-authored 4 publications.
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Papers
The Deubiquitinating Enzyme UCHL1 Induces Resistance to Doxorubicin in HER2+ Breast Cancer by Promoting Free Fatty Acid Synthesis.
Guangxian Lu,Jianhua Li,Leyun Ding,Chenping Wang,Lian Tang,Xin Liu,Jinhui Xu,Qin Zhou,Jiantong Sun,Wenjuan Wang,Xinyuan Ding +10 more
TL;DR: In this article, up-regulated UCHL1 expression was positively associated with both chemoresistance and poor prognosis, especially in patients with HER2+ BC, and it was shown that UCHL 1 up-regulation probably promoted DOX-resistance of BC by up-regulating free fatty acid (FFA) synthesis.
Corrigendum: USP5 Promotes Metastasis in Non-Small Cell Lung Cancer by Inducing Epithelial-Mesenchymal Transition via Wnt/β-Catenin Pathway.
Sudong Xue,Wei Wu,Ziyan Wang,Guangxian Lu,Jiantong Sun,Xing Jin,Lin-Jun Xie,Xiaoyu Wang,Caihong Tan,Zheng Wang,Wenjuan Wang,Xinyuan Ding +11 more
TL;DR: Overall, USP5 upregulation is associated with tumor metastasis and poor prognosis in patients with NSCLC, and may serve as a novel prognostic biomarker and provide a potential target for the treatment of metastasis inNSCLC.
A Regression Model to Predict Augmented Renal Clearance in Critically Ill Obstetric Patients and Effects on Vancomycin Treatment
Lian Tang,Xinyuan Ding,Lu-fen duan,Lan Li,Hao-di Lu,Feng Zhou,Lu Shi,Jian Lu,Yi Shen,Zhiwei Zhuang,Jiantong Sun,Qin Zhou,Chen-qi Zhu,Jingjing Li,Yanxia Yu +14 more
TL;DR: In this paper, a regression model for predicting augmented renal clearance (ARC) risk factors and effects on vancomycin (VCM) of obstetric patients were possibly different from other populations based on pathophysiological characteristics.
Neuronal Nitric Oxide Synthase in Neural Stem Cells Induces Neuronal Fate Commitment via the Inhibition of Histone Deacetylase 2.
TL;DR: It is reported that endogenous neuronal nitric oxide synthase for neural stem cells (NSCs) or progenitors positively regulates neurogenesis, and instructive effect, that is instruction of NSCs to adopt a neuronal fate, contributes to the favorable effect of endogenous nNOS on neuroGenesis.