Xinna Zhang
Indiana University
95 Papers
387 Citations
Xinna Zhang is an academic researcher from Indiana University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 41, co-authored 75 publications. Previous affiliations of Xinna Zhang include University of South Carolina & University of Texas MD Anderson Cancer Center.
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Papers
Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells
Pinar Kanlikilicer,Mohammed H. Rashed,Mohammed H. Rashed,Recep Bayraktar,Rahul Mitra,Cristina Ivan,Burcu Aslan,Xinna Zhang,Justyna Filant,Andreia M. Silva,Cristian Rodriguez-Aguayo,Emine Bayraktar,Martin Pichler,Martin Pichler,Bulent Ozpolat,George A. Calin,Anil K. Sood,Gabriel Lopez-Berestein +17 more
TL;DR: It is reported that miR-6126 is ubiquitously released in high abundance from both chemosensitive and chemoresistant ovarian cancer cells via exosomes, providing new insights into the role of exosomal miRNA-mediated tumor progression and suggesting a new therapeutic approach to disrupt oncogenic phenotypes in tumors.
Association between hemoglobin concentration and hypertension risk in native Tibetans at high altitude.
Xueting Liu,Changqiang Yang,Xinna Zhang,Runyu Ye,Xinran Li,Zhipeng Zhang,Shanshan Jia,Lirong Sun,Qingtao Meng,Xiao Chen +9 more
TL;DR: Hemoglobin concentration was associated with hypertension risk in native Tibetans at high altitude and when the hemoglobin concentration exceeded a certain value, the risk of hypertension was significantly increased.
Manganese Dioxide‐Based Nanocarrier Delivers Paclitaxel to Enhance Chemotherapy against Orthotopic Glioma through Hypoxia Relief
Shuqi Jiang,Xiaochun Li,Fang Zhang,Jiaji Mao,Minghui Cao,Xinna Zhang,Siming Huang,Xiaohui Duan,Jun Shen +8 more
TL;DR: A new class of tLyP‐1‐modified dopamine (DOPA)‐β‐cyclodextrin (CD)‐coated paclitaxel (PTX)‐ and manganese dioxide (MnO2)‐loaded nanoparticles (tLyP•1‐CD‐DOPA‐Mn o2@ PTX) is developed to enhance glioma chemotherapy and enable real‐time tumor monitoring with magnetic resonance imaging.
Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid
M. Andreeff,Shuwei Jiang,Xinna Zhang,Marina Konopleva,Zeev Estrov,Virginia Snell,Zhong Xie,M. F. Okcu,Gisela Sanchez-Williams,J. Dong,Eli Estey,R. C. Champlin,Steve Kornblau,John C. Reed,Shourong Zhao +14 more
TL;DR: Surprisingly, low Bcl-2 content was associated with poor survival in a group of patients with poor prognosis cytogenetics and the development of new therapeutic strategies for AML are discussed.
Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer
Martin Pichler,Cristian Rodriguez-Aguayo,Su Youn Nam,Mihnea P. Dragomir,Recep Bayraktar,Simone Anfossi,Erik Knutsen,Cristina Ivan,Enrique Fuentes-Mattei,Sang Kil Lee,Hui Ling,Tina Catela Ivkovic,Guoliang Huang,Li Huang,Yoshinaga Okugawa,Hiroyuki Katayama,Ayumu Taguchi,Emine Bayraktar,Rajat Bhattacharya,Paola Amero,William Ruixian He,Anh M. Tran,Petra Vychytilova-Faltejskova,Christiane Klec,Diana L. Bonilla,Xinna Zhang,Sanja Kapitanović,Bozo Loncar,Roberta Gafà,Zhihui Wang,Vittorio Cristini,Samir M. Hanash,Menashe Bar-Eli,Giovanni Lanza,Ondrej Slaby,Ajay Goel,Isidore Rigoutsos,Gabriel Lopez-Berestein,George A. Calin +38 more
TL;DR: FLANC is discovered as a novel primate-specific lncRNA that is highly upregulated in CRC cells and regulates metastases formation, and may represent a novel and low toxic therapeutic strategy for the treatment of patients.