Xin Wang
Chengdu Medical College
6 Papers
2 Citations
Xin Wang is an academic researcher from Chengdu Medical College. The author has contributed to research in topics: Dopamine receptor D1 & (+)-Naloxone. The author has an hindex of 3, co-authored 6 publications.
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Papers
The therapeutic potential of attenuated diphtheria toxin delivered by an adenovirus vector with survivin promoter on human lung cancer cells.
Lvxia Dai,Xiaoping Yu,Sizhou Huang,Yanjuan Peng,Jian-Min Liu,Tian Chen,Xin Wang,Qiaofeng Liu,Yanfeng Zhu,Deng-bang Chen,Xiaohua Li,Yu Ou,Yi Zou,Qu Pan,Kang Cao +14 more
TL;DR: In this paper, the authors compared the three kinds of recombinant adenoviruses that carry DTA or its attenuated forms (DTA176 and DTA197) in the treatment of human lung cancer.
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Minocycline alleviates the symptoms of morphine withdrawal via the CaMKII-Ras-ERK signaling pathway.
TL;DR: In this article, minocycline was injected into the midbrain periaqueductal gray and its effect on withdrawal symptoms and Ca2+-dependent protein kinase (CaMKII), Ras, and p-ERK expression was observed.
5
Injection of D1 receptor antagonist SCH23390 into the periaqueductal gray attenuates morphine withdrawal symptoms in rats.
TL;DR: The results suggest that D1R antagonist decreased the withdrawal response in morphine-exposed rats by downregulating the downstream factors, CaMKII, p-ERK and CREB.
2
Injection of Toll-like receptor 4 siRNA into the ventrolateral periaqueductal gray attenuates withdrawal syndrome in morphine-dependent rats.
TL;DR: Findings indicate that modifying TLR4 gene expression in the vlPAG stimulates expression of the downstream signaling molecule, GAD67, which decreases Glu levels and increases GABA levels, which may explain the inhibition of withdrawal syndrome in morphine-dependent rats.
Dopamine D1 receptor agonist treatment alleviates morphine-exposure-induced learning and memory impairments.
Qiaofeng Liu,Xuemei Li,Yanshuang Zhao,Kang Cao,Yang Liu,Rui Xiao,Chenyi Wang,Yanxia Li,Wenli Huang,Xin Wang +9 more
TL;DR: Administration of the dopamine D1 receptor agonist SKF81297 into the PAG alleviated morphine-exposure-induced cognitive impairments and improved learning and memory ability in morphine-treated rats.