Xin Wang
Kettering University
7 Papers
Xin Wang is an academic researcher from Kettering University. The author has contributed to research in topics: Nucleosome & Chromatin. The author has an hindex of 6, co-authored 6 publications.
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Papers
A RSC/Nucleosome Complex Determines Chromatin Architecture and Facilitates Activator Binding
Monique Floer,Xin Wang,Vidya Prabhu,Georgina Berrozpe,Santosh Narayan,Dan Spagna,David Alvarez,Jude Kendall,Alexander Krasnitz,Asya Stepansky,James W. Hicks,Gene O. Bryant,Mark Ptashne +12 more
TL;DR: The results show that both prior to and following induction, specific DNA-binding proteins are the predominant determinants of chromatin architecture at the GAL1/10 genes.
193
Nucleosome Avidities and Transcriptional Silencing in Yeast
TL;DR: The quantitative nucleosome occupancy assay is used to show that Sirs (which bind nucleosomes) increase the avidities with which thoseucleosomes form at the promoters, which can account for at least part of the repressive effects of the Sirs and can explain why silencing is effective in countering weak activation only.
18
Nucleosomes and the accessibility problem
TL;DR: Evidence is cited against the idea that nucleosome positioning is determined primarily by the intrinsic propensities of DNA sequences to form nucleosomes--such that, for example, regulatory sites would be 'nucleosome-free', and studies in yeast show that nucleosity positioning is primarily determined by specific DNA-binding proteins.
Cytogenetic analysis of 2959 couples with spontaneous abortion and detailed analysis of rare karyotypes
TL;DR: The sex of patients with chromosomal abnormalities and the number of spontaneous abortions should be considered in genetic counselling, as chromosome abnormality could be one of the important causes of spontaneous abortion in Yantai, Shandong province, China.
Activator control of nucleosome occupancy in activation and repression of transcription.
TL;DR: The results show how an activator's recruiting function can control chromatin structure both during gene activation and repression, and show that whereas promoter nucleosome removal invariably accompanies activation, reformation of nucleosomes is not required for repression.