Xin Wang
Shanghai Jiao Tong University
9 Papers
34 Citations
Xin Wang is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Medicine & Bone marrow. The author has an hindex of 4, co-authored 4 publications.
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Papers
Bone Mesenchymal Stem Cell-Enriched β-Tricalcium Phosphate Scaffold Processed by the Screen-Enrich-Combine Circulating System Promotes Regeneration of Diaphyseal Bone Non-Union.
Xin Wang,Wenxiang Chu,Yifu Zhuang,Dingwei Shi,HaiRong Tao,Chen Jin,Kerong Dai,Jie Zhao,Yaokai Gan +8 more
TL;DR: The SECCS could concentrate a large proportion of MSCs from bone marrow to acquire enough effective cells for therapy without in vitro cell culture and showed a satisfactory clinical curative effect for diaphyseal bone non-union, which was non-inferior to AGT.
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Mesenchymal stem cells and porous β-tricalcium phosphate composites prepared through stem cell screen-enrich-combine(−biomaterials) circulating system for the repair of critical size bone defects in goat tibia
TL;DR: A novel stem cell screen-enrich-combine(−biomaterials) circulating system (SECCS) was introduced to provide the substitutes with osteogenic ability and demonstrated significant therapeutic efficacy in goat models of critical size bone defect.
DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1‐Mediated NRF2 Ubiquitination
Xin Wang,Tangjun Zhou,Xiao Yang,Xiankun Cao,Gu Jin,Pu Zhang,Jiadong Guo,Kewei Rong,Baixing Li,Kexin Liu,Peixiang Ma,An Qin,Jie‐Zu Zhao +12 more
TL;DR: In this article , the authors found that DDRGK domain-containing protein 1 (DDRGK1) plays a fundamental role in chemoresistance induced in osteosarcoma.
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Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways
Baixing Li,Xiao Yang,Pu Zhang,Jiadong Guo,Kewei Rong,Xin Wang,Xiankun Cao,Tangjun Zhou,Jie‐Zu Zhao +8 more
TL;DR: It is found that the activation of MAPK and NF-κB signaling pathways and the nuclear translocation of phosphorylated p65 and p38 were inhibited prominently with the treatment of engeletin which may be the potential molecular mechanism for its anti-inflammation effects.
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Specific PFKFB3 Inhibitor Memorably Ameliorates Intervertebral Disc Degeneration via Inhibiting NF-κB and MAPK Signaling Pathway and Reprogramming of Energy Metabolism of Nucleus Pulposus Cells
Xiankun Cao,Xin Wang,Kewei Rong,Kexin Liu,Xiao Yang,Tangjun Zhou,Pu Zhang,Jiadong Guo,Hui Ma,An Qin,Jie Zhao +10 more
TL;DR: In vitro KAN toxicity in NP primary cells (NPPs) authenticated the potential therapeutic effect of KAN on IVDD and declaimed its mechanisms of both novel energy metabolism reprogramming and conventional anti-inflammation effect.
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