25 Papers
94 Citations
Xin Fu is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Embryonic stem cell & Mesenchymal stem cell. The author has an hindex of 12, co-authored 25 publications. Previous affiliations of Xin Fu include National University of Singapore.
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Papers
Adipose-Derived Mesenchymal Stem Cells from the Elderly Exhibit Decreased Migration and Differentiation Abilities with Senescent Properties.
Meichen Liu,Hua Lei,Ping Dong,Xin Fu,Zhigang Yang,Ying Yang,Jiguang Ma,Xia Liu,Yilin Cao,Ran Xiao +9 more
TL;DR: The results suggest that, while hASCs from different age populations are phenotypically similar, they present major differences at the functional level, and the negative influence of age on hASC differentiation potential and migration abilities should be taken seriously.
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TGF-β1 Induces Polypyrimidine Tract-Binding Protein to Alter Fibroblasts Proliferation and Fibronectin Deposition in Keloid.
Hu Jiao,Ping Dong,Li Yan,Zhigang Yang,Xiaoyan Lv,Qiuchen Li,Xianlei Zong,Jincai Fan,Xin Fu,Xia Liu,Ran Xiao +10 more
TL;DR: Evidence is provided for the role of PTB in keloid pathophysiology and the role TGF-β1 regulation ofPTB may provide new insights into the mechanisms underlying inflammatory cytokine-induced fibrosis.
Differentiated fibroblastic progenies of human embryonic stem cells for toxicology screening.
TL;DR: PH9 exhibited a more sensitive dose-response to mitomycin C compared to L929, which could be advantageous for cytotoxicity screening assays, and it was demonstrated that a highly purified and well-defined phenotypic population of differentiated hESC progenies is not necessary for high reproducibility and accuracy in cytotoxic response.
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Influence of Immunogenicity of Allogeneic Bone Marrow Mesenchymal Stem Cells on Bone Tissue Engineering
Jingguo Wu,Qian Wang,Xin Fu,Xiaowei Wu,Congmin Gu,Jianhai Bi,Fangnan Xie,Ning Kang,Xia Liu,Li Yan,Yilin Cao,Ran Xiao +11 more
TL;DR: It is indicated that allo-BMSCs can induce a transient immunoreaction, which may temporally delay the osteogenesis of allo -BMSC/scaffold complex in early stage of in vivo implantation, whereas the long-term engineered bone formation was not affected.
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Short communication An autologous cell lysate extract from human embryonic stem cell (hESC) derived osteoblasts can enhance osteogenesis of hESC
Boon Chin Heng,Wei Seong Toh,Barry P. Pereira,Bee Leng Tan,Xin Fu,Hua Liu,Kathy Lu,Jin-Fei Yeo,Tong Cao +8 more
- 01 Jan 2008
TL;DR: In this paper, an autologous osteogenic-inducing culture supplement extracted from hESC-derived osteogenic cells themselves was used to further enhance the osteogenesis of hESCs, which would save costs from the use of highly expensive cytokines, growth factors and matrix components.
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