5 Papers
104 Citations
Xin Cai is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: Spindle apparatus & Mitosis. The author has an hindex of 4, co-authored 5 publications. Previous affiliations of Xin Cai include Morehouse School of Medicine.
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Papers
Human NUF2 Interacts With Centromere-Associated Protein E and Is Essential for a Stable Spindle Microtubule-Kinetochore Attachment
Dan Liu,Xia Ding,Xia Ding,Jian Du,Xin Cai,Xin Cai,Yuejia Huang,Tarsha Ward,Andrew P. Shaw,Yong Yang,Yong Yang,Renming Hu,Changjiang Jin,Xuebiao Yao,Xuebiao Yao +14 more
TL;DR: It is shown that Homo sapiens (Hs) NUF2 is required for stable kinetochore localization of centromere-associated protein E (CENP-E) in HeLa cells and that depletion of HsNUF2 caused aberrant chromosome segregation.
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Human NUF2 Interacts with Centromere-associated Protein E and Is Essential for a Stable Spindle
Dan Liu,Xia Ding,Jian Du,Xin Cai,Yuejia Huang,Tarsha Ward,Andrew W. Shaw,Yong Yang,Renming Hu,Changjiang Jin,Xuebiao Yao +10 more
- 01 Jan 2007
TL;DR: In this paper, the authors show that HsNUF2 is required for stable kinetochore localization of centromere-associated protein E (CENP-E) in HeLa cells.
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Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis
Guosheng Fu,Xia Ding,Kai Yuan,Felix O. Aikhionbare,Jianhui Yao,Xin Cai,Kai Jiang,Xuebiao Yao +7 more
TL;DR: It is proposed that NEK2A-mediated phosphorylation of human Sgo1 provides a link between centromeric cohesion and spindle microtubule attachment at the kinetochores and is essential for faithful chromosome congression in mitosis.
Interaction of Skp1 with CENP-E at the midbody is essential for cytokinesis
Dan Liu,Ning Zhang,Jian Du,Xin Cai,Mei Zhu,Changjiang Jin,Zhen Dou,Zhen Dou,Cijian Feng,Ye Yang,Li Liu,Kunio Takeyasu,Wei Xie,Xuebiao Yao,Xuebiao Yao +14 more
TL;DR: It is hypothesized that CENP-E degradation is essential for faithful mitotic exit and the proteolysis of CENp-E is mediated by SCF via a direct Skp1 link.
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An efficient site-directed mutagenesis method for ColE1-type ori plasmid.
TL;DR: A single inverse PCR with two primers method for site-directed mutagenesis is very simple and rapid, but the practical application is generally limited to the relatively small-sized plasmid and depends largely on efficiency and fidelity of the polymerase.
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