Xiaoyu Wang
Nanjing Medical University
6 Papers
Xiaoyu Wang is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Medicine & Cancer research. The author has an hindex of 1, co-authored 1 publications.
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Papers
Platinum-based TREM2 Inhibitor Suppresses Tumor via Remodeling Immunosuppressive Microenvironment.
Xiaoyong Wang,Tao Yang,Shuren Zhang,Hao-liang Yuan,Ying Wang,Linxiang Cai,Hanhua Chen,Xiaoyu Wang,Dongfan Song,Xiaohui Wang,Zijian Guo +10 more
- 19 Oct 2022
TL;DR: OPA is the first small-molecular TREM2 inhibitor capable of relieving immunosuppressive tumor microenvironment and enhancing chemical anticancer efficiency of platinum drug, thus showing typical characteristics of a chemoimmunotherapeutic agent.
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The immunosuppressive microenvironment and immunotherapy in human glioblastoma
Xuehua Zhang,Leilei Zhao,Hecui Zhang,Yurui Zhang,Huanyu Ju,Xiaoyu Wang,Huan Ren,Xiao Zhu,Yucui Dong +8 more
TL;DR: In this article , the key immunosuppressive components in the tumor microenvironment, along with the regulatory mechanism of the gut microbiota involved in immunity and metabolism in the GBM microenvironment are discussed.
IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma
Xuehua Zhang,Guoyan Wang,Yujiao Gong,Leilei Zhao,Ping Song,Hecui Zhang,Yurui Zhang,Huanyu Ju,Xiaoyu Wang,Bin Wang,Huan Ren,Xiao Zhu,Yucui Dong +12 more
TL;DR: In this article , the insulin-like growth factor binding protein-3 (IGFBP3) was considered a candidate, whereas the mechanisms of IGFBP3 production remain unclear.
19
Solasodine suppresses the metastasis of gastric cancer through claudin-2 via the AMPK/STAT3/NF-κB pathway.
TL;DR: In this paper , the role and mechanism of solasodine in inhibiting Gastric cancer (GC) metastasis was investigated, and it was shown that solasoda not only promoted cell death but also inhibited the migration and invasion of HGC27 and AGS cells.
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Corrigendum: USP5 Promotes Metastasis in Non-Small Cell Lung Cancer by Inducing Epithelial-Mesenchymal Transition via Wnt/β-Catenin Pathway.
Sudong Xue,Wei Wu,Ziyan Wang,Guangxian Lu,Jiantong Sun,Xing Jin,Lin-Jun Xie,Xiaoyu Wang,Caihong Tan,Zheng Wang,Wenjuan Wang,Xinyuan Ding +11 more
TL;DR: Overall, USP5 upregulation is associated with tumor metastasis and poor prognosis in patients with NSCLC, and may serve as a novel prognostic biomarker and provide a potential target for the treatment of metastasis inNSCLC.