Xiaoyan Lin
Shandong University
7 Papers
2 Citations
Xiaoyan Lin is an academic researcher from Shandong University. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 4, co-authored 5 publications.
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Papers
Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol
Yanjing Guo,Meng Zhao,Tao Bo,Shizhan Ma,Zhongshang Yuan,Wenbin Chen,Zhao He,Xu Hou,Jun Liu,Zhenhai Zhang,Qiang Zhu,Qiangxiu Wang,Xiaoyan Lin,Zhongli Yang,Cui Min,Lu Liu,Yujie Li,Chunxiao Yu,Xiaoyi Qi,Qian Wang,Haiqing Zhang,Qingbo Guan,Lifang Zhao,Shi-meng Xuan,Huili Yan,Yanliang Lin,Li Wang,Qihang Li,Yongfeng Song,Ling Gao,Jiajun Zhao +30 more
TL;DR: It is found that blocking FSH reduces serum cholesterol via inhibiting hepatic cholesterol biosynthesis and might be a new strategy for treating hypercholesterolemia during menopause, particularly for women in peri-menopause characterized by FSH elevation only.
Characterization of a Relatively Malignant form of Osteopetrosis Caused by a Novel Mutation in the PLEKHM1 Gene
Tao Bo,Fang Yan,Jun Guo,Xiaoyan Lin,Haiqing Zhang,Qingbo Guan,Hai Wang,Li Fang,Ling Gao,Jiajun Zhao,Chao Xu +10 more
TL;DR: A four‐year follow‐up study of the patient showed that the PLEKHM1‐dependent osteopetrosis was relatively malignant, with significant symptoms of pancytopenia and hepatosplenomegaly.
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Response to Pralsetinib in Multi-Drug-Resistant Breast Cancer With CCDC6-RET Mutation
Jing Zhao,Wei Xu,X. Zhuo,Lei Liu,Junlei Zhang,Fengxian Jiang,Yan Lei,Dongsheng Hou,Xiaoyan Lin,Cuiyan Wang,Guobin Fu +10 more
TL;DR: In this paper , the authors used next-generation sequencing (NGS) to find drug mutation targets, which revealed a coiled-coil domain-containing protein 6 (CCDC6)-rearranged during transfection (RET) gene fusion mutation.
Presence of serum autoantibodies to vacuolar H+ -ATPase in patients with renal tubular acidosis.
TL;DR: This study aimed to detect the serum antibodies to renal tubular epithelial cells in RTA patients and found no evidence of immune factors in the pathogenesis of RTA.
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Potential mechanism of pyrotinib-induced diarrhea was explored by gut microbiome and ileum metabolomics
J. Lai,X. Zhuo,Kemin Yin,Fengxian Jiang,Lei Liu,Xiaoying Xu,Hongjing Liu,Jing-liang Wang,Jing Zhao,Wei Xu,Shuping Yang,Honglin Guo,Xiaotian Yuan,Xiaoyan Lin,Fanghua Qi,Guobin Fu +15 more
TL;DR: In this paper , the effects of different doses of pyrotinib (20, 40, 60, 80 and 80 mg/kg) in Wistar rats were compared, and the mechanism underlying the mechanism was fully studied using gut microbiome and host intestinal tissue metabolomics profiling.
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