Xiaoyan Bai
Southern Medical University
22 Papers
1 Citations
Xiaoyan Bai is an academic researcher from Southern Medical University. The author has contributed to research in topics: Lung cancer & Tubulointerstitial fibrosis. The author has an hindex of 15, co-authored 19 publications.
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Papers
MicroRNA-130b improves renal tubulointerstitial fibrosis via repression of Snail-induced epithelial-mesenchymal transition in diabetic nephropathy.
TL;DR: A novel role of the miR-130b-SNAIL axis is proposed in fostering EMT and progression toward increased tubulointerstitial fibrosis in DN and its association with SNAIL can be extrapolated to quantifying the severity of renal tubuloInterstitial fibrosis.
Advanced Oxidation Protein Products Promote Lipotoxicity and Tubulointerstitial Fibrosis via CD36/β-Catenin Pathway in Diabetic Nephropathy.
Xiao Li,Ting Zhang,Jian Geng,Zhuguo Wu,Liting Xu,Jixing Liu,Jianwei Tian,Zhanmei Zhou,Jing Nie,Xiaoyan Bai +9 more
TL;DR: A major role of AOPPs is revealed in triggering lipotoxicity and fibrosis via CD36-dependent Wnt/β-catenin activation, providing new evidences for understanding the role of lipid accumulation in DN.
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Advanced Oxidation Protein Products Aggravate Tubulointerstitial Fibrosis Through Protein Kinase C-Dependent Mitochondrial Injury in Early Diabetic Nephropathy.
TL;DR: A novel mechanism is proposed that AOPPs-induced mitochondrial dysfunction and oxidative stress cause TIF in DN via activation of the PKCη isoform.
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Efficacy comparison of atorvastatin versus rosuvastatin on blood lipid and microinflammatory state in maintenance hemodialysis patients.
TL;DR: The results have shown that ROS is better than ATO in the treatment of MHD patients, and ATO and ROS not only decreased blood lipid levels but also inhibited the microinflammatory state and improved nutrition situation in M HD patients.
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MicroRNA-130b Improves Renal Tubulointerstitial Fibrosis via Repression of Snail-Induced Epithelial-Mesenchymal Transition in Diabetic Nephropathy
TL;DR: In this paper, the role and mechanisms for miR-130b in mediating renal tubulointerstitial fibrosis in diabetic nephropathy (DN) remain unknown, but miR130b downregulation exhibited clinical and biological relevance as it was linked to increased serum creatinine, β2-microglobulin and proteinuria, increased Snail expression and tubulostitial fibrosis.
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