Xiaoxue Ma
China Medical University (PRC)
24 Papers
10 Citations
Xiaoxue Ma is an academic researcher from China Medical University (PRC). The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 3, co-authored 6 publications. Previous affiliations of Xiaoxue Ma include University of Occupational and Environmental Health Japan.
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Papers
Janus Kinase Inhibitor Baricitinib Modulates Human Innate and Adaptive Immune System.
Satoshi Kubo,Shingo Nakayamada,Kei Sakata,Yukihiro Kitanaga,Xiaoxue Ma,Seunghyun Lee,Akina Ishii,Kaoru Yamagata,Kazuhisa Nakano,Yoshiya Tanaka +9 more
TL;DR: Baricitinib suppresses the differentiation of plasmablasts, Th1 and Th17 cells, as well as innate immunity, such as the T cell stimulatory capacity of dendritic cells, which indicates that JAK inhibitors can be potentially clinically effective not only in rheumatoid arthritis but other immune-related diseases.
Type I and II interferons commit to abnormal expression of chemokine receptor on B cells in patients with systemic lupus erythematosus.
Maiko Yoshikawa,Shingo Nakayamada,Satoshi Kubo,Aya Nawata,Yukihiro Kitanaga,Shigeru Iwata,Kei Sakata,Xiaoxue Ma,Sheau Pey Wang,Kazuhisa Nakano,Kazuyoshi Saito,Yoshiya Tanaka +11 more
TL;DR: Qualitative abnormalities accompanying reduced CXCR5 expression via type I IFN and enhanced CX CR3 expression viatype II IFN in SLE are revealed, suggesting their involvement in B cell infiltration into tissues and inflammatory pathogenesis.
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The ILEI/LIFR complex induces EMT via the Akt and ERK pathways in renal interstitial fibrosis
Jie Zhou,Hong-Kun Jiang,Hongkun Jiang,Yanling Fan,Jiwang Zhang,Xiaoxue Ma,Xue-wei Yang,Yu Sun,Xing Zhao +8 more
TL;DR: In this article , the authors investigated the role of interleukin-like EMT inducer (ILEI) in triggering renal interstitial fibrosis (RIF) in children with chronic kidney disease (CKD).
Time-spatial analysis of T cell receptor repertoire in esophageal squamous cell carcinoma patients treated with combined radiotherapy and PD-1 blockade
Cihui Yan,Xiaoxue Ma,Zhoubo Guo,Xiaoying Wei,Dong Han,Tian-Ze Zhang,Xi Chen,Fu-liang Cao,Jie Dong,Gang Zhao,Xuan Gao,Tao Wang,Yao Jiang,Ping Wang,Qingsong Pang,Wencheng Zhang +15 more
TL;DR: Radiotherapy combined with PD-1 blockade greatly promoted time-spatial alteration of TCR repertoire between tumor and peripheral blood, which demonstrate the peripheral CD8+ TCR diversity at baseline and dynamic alteration of intratumoral TCRs acted as potential effective biomarkers of radiotherapy Combined with immunotherapy in ESCC.
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Competitive Binding of Transcription Factors Underlies Flexibility of T Peripheral Helper Cells and T Follicular Helper Cells in SLE.
Qinglian Jiang,Jiakai Wang,Hong-Kun Jiang,Wei Li,Yini Sun,Yu Shan,Tong Wei,Xuyang Chi,S. Yu,Xiaoxue Ma +9 more
TL;DR: The finding that synergy of IFN-α and IL-2 increases Tph cells through competitive transcriptional regulation, could be one of the mechanisms responsible for pathologic formation of ELSs and helpful for selection of individualized therapeutic approaches for SLE.
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