Xiaoxia Jin
Cleveland Clinic
6 Papers
19 Citations
Xiaoxia Jin is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: Magnetization & Hep G2. The author has an hindex of 6, co-authored 6 publications. Previous affiliations of Xiaoxia Jin include Ohio State University & Cleveland Clinic Lerner Research Institute.
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Papers
Femtogram Resolution of Iron Content on a Per Cell Basis: Ex Vivo Storage of Human Red Blood Cells Leads to Loss of Hemoglobin
Jeffrey J. Chalmers,Xiaoxia Jin,Xiaoxia Jin,Andre F. Palmer,Mark H. Yazer,Lee R. Moore,Peter Amaya,Kyoung-Joo Jenny Park,X. Pan,Maciej Zborowski +9 more
TL;DR: Using a previously developed and reported instrument, cell tracking velocimetry (CTV), this Article is able to detect difference in Hb concentration in two RBC populations to a resolution of 1 × 107 Hb molecules per cell, the result of routine RBC storage.
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Iron Transport in Cancer Cell Culture Suspensions Measured by Cell Magnetophoresis
TL;DR: The method is tested on cells with less obvious paramagnetic properties: cell cultures derived from human cancers to determine if the magnetophoretic mobility measurement is sufficiently sensitive to the dysregulation of the intracellular iron metabolism as suggested by reports on loss of iron homeostasis in cancer.
Quantification of changes in oxygen release from red blood cells as a function of age based on magnetic susceptibility measurements
TL;DR: The decrease in magnetophoretic mobility of the deoxyHb portion is explicable either by Hb's increased affinity for oxygen during storage, or else a loss of iron from the cells.
Erythrocyte enrichment in hematopoietic progenitor cell cultures based on magnetic susceptibility of the hemoglobin.
Xiaoxia Jin,Xiaoxia Jin,Stewart Abbot,Xiaokui Zhang,Lin Kang,Vanessa Voskinarian-Berse,Rui Zhao,Marina V. Kameneva,Lee R. Moore,Jeffrey J. Chalmers,Maciej Zborowski +10 more
TL;DR: The results demonstrate feasibility of label-free magnetic enrichment of erythrocyte fraction of CD34+ progenitor-derived cultures based on the presence of paramagnetic hemoglobin in the maturing ery Throcytes.
Differences in magnetically induced motion of diamagnetic, paramagnetic, and superparamagnetic microparticles detected by cell tracking velocimetry.
Xiaoxia Jin,Xiaoxia Jin,Yang Zhao,Aaron Richardson,Lee R. Moore,P. Stephen Williams,Maciej Zborowski,Jeffrey J. Chalmers +7 more
TL;DR: Sensitivity of the CTV analysis to different magnetization mechanisms of the microparticles is demonstrated, producing a value of MM independent of the applied H field for the paramagnetic species, and a decreasing MM value with an increasing field for superparamagnetic species.