Xiaowei Shi
Zhejiang Chinese Medical University
5 Papers
4 Citations
Xiaowei Shi is an academic researcher from Zhejiang Chinese Medical University. The author has contributed to research in topics: Drug delivery & Nanocarriers. The author has an hindex of 4, co-authored 5 publications.
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Papers
iRGD and TGN co-modified PAMAM for multi-targeted delivery of ATO to gliomas.
Xiaowei Shi,Rui Ma,Yanping Lu,Ying Cheng,Xudong Fan,Jiafeng Zou,Hongyue Zheng,Fanzhu Li,Ji-Gang Piao +8 more
TL;DR: iRGD/TGN-based dual targeting by combining nanocarriers and targeting technology increased the amount of drug that crossed BBB, thus achieving targeted enrichment and activation of the drug in tumor tissue, and shows great promise for targeted glioma therapy.
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The Effect of Size on the Surface Enhanced Raman Scattering Property of SiO2@PDA@AgNP Core-Shell-Satellite Nanocomposite
TL;DR: SiO2@PDA@AgNP core-shell-satellite nanostructure as a new SERS substrate was reported by in situ deposition of silver nanoparticles (AgNP) on the surface of polydopamine (PDA) c....
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Sustained-release study on Exenatide loaded into mesoporous silica nanoparticles: in vitro characterization and in vivo evaluation
TL;DR: This study demonstrates that the EXT-SBA-15 delivery system can control the sustainability of EXT and contribute to improve EXT clinical use.
A novel synergetic targeting strategy for glioma therapy employing borneol combination with angiopep-2-modified, DOX-loaded PAMAM dendrimer
Han Shunping,Hongyue Zheng,Yanping Lu,Yue Sun,Huang Anhao,Weidong Fei,Xiaowei Shi,Xu Xiuling,Li Jingjing,Fanzhu Li +9 more
TL;DR: Results demonstrated that Angiopep-2 modification could actually enhance the affinity between the dendrimers and the targeting cells and finally increase the cell uptake and boost the anti-tumour ability of this targeting drug delivery system (TDDS) after penetrating BBB.
A single-label fluorescent derivatization method for quantitative determination of neurotoxin in vivo by capillary electrophoresis coupled with laser-induced fluorescence detection
Cuiwei Chen,Hu Yiqin,Xiaowei Shi,Chenghao Tao,Hongyue Zheng,Weidong Fei,Han Shunping,Jiazhen Zhu,Yinghui Wei,Fanzhu Li +9 more
TL;DR: The established method robustly and reliably quantified NT labelled with FITC via intravenous and intramuscular administrations in vivo and fully demonstrated the pharmacokinetic characteristics ofNT in vivo, which could reduce the risk of drug accumulation, optimize therapies, and provide sufficient evidence for the rational use of NT in clinical and research laboratories.